Results 121 to 130 of about 251,076 (337)

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson   +8 more
wiley   +1 more source

Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐threatening psychiatric events in some individuals.
Amy G. McNeilage   +4 more
wiley   +1 more source

Integrating Astrocytes in the Sleep–Wake Cycle: The Time Is Now

open access: yesBioEssays, EarlyView.
Astrocytes actively regulate sleep homeostatic and circadian rheostatic processes, underpinning the sleep–wake cycle. By acting as context‐dependent integrators of internal state and rhythmic environmental inputs, they modulate the encoding properties of neuronal circuitries and contribute to salient temporal representations in the brain.
Marco Brancaccio
wiley   +1 more source

Increased Response Variability and Attentional Lapses After Chronic Cocaine Self-Administration [PDF]

open access: yes, 2009
In humans, cocaine use has long been associated with poor attentional control and decreased efficiency in goal-oriented behavior. Animal models of these stereotypic drug effects, however, have thus far failed to produce quantifiable data sets in part ...
Olsen, Adam
core  

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

Prevalence and Prognostic Impact of Coronary Chronic Total Occlusions in Patients With Cardiogenic Shock

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mortality in patients with cardiogenic shock (CS) remains high despite advanced treatment strategies in CS patients, underlining the need for the identification of predictors of prognosis in CS patients. Therefore, the present study investigates the prognostic impact of coronary chronic total occlusions (CTO) in patients with CS ...
Michael Behnes   +15 more
wiley   +1 more source

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