Results 131 to 140 of about 332,122 (357)

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Tyr-Trp administration facilitates brain norepinephrine metabolism and ameliorates a short-term memory deficit in a mouse model of Alzheimer’s disease

, 2020
Takashi Ichinose, Hiroyasu Murasawa, Tomoko Ishijima, Shinji Okada, Keiko Abe, Saki Matsumoto, Toshiro Matsui, Shigeki Furuya   +7 more
openalex   +2 more sources

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye, Rui Zhang, Jing Wan, Jinping Zhou, Pengpeng Guo, Dianwen Yu, Peixia Li, Yani Liu, Shaojun Shi   +8 more
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation as a potential therapy for attention deficit hyperactivity disorder: modulation of the noradrenergic pathway in the prefrontal lobe

Frontiers in Neuroscience
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by developmental impairments, inattention, motor hyperactivity, and impulsivity. Currently, there is no effective intervention that can completely cure it. One
Jincao Zhi, Shiwen Zhang, Meiling Huang, Huan Qin, He Xu, Qing Chang, Yan Wang   +6 more
doaj   +1 more source

Clinical Experience with Norepinephrine (NE) Infusions in Critically Ill Newborns. 856 [PDF]

, 1997
Douglas P. Derleth
openalex   +1 more source

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Hemodynamic Management with Vasopressin for Cardiovascular Surgery

Medicina
Background and Objectives: Vasopressin increases blood pressure through aquaporin-2-mediated water retention and is useful for managing hemodynamics after surgery.
Hideyuki Kato, Bryan J. Mathis, Tomonari Shimoda, Tomomi Nakajima, Chiho Tokunaga, Yuji Hiramatsu   +5 more
doaj   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Sensing norepinephrine [PDF]

Nature Methods, 2019
openaire   +2 more sources

Norepinephrine Involvment in Penile Detumescence [PDF]

, 1990
Diederichs, W., Lue, Tom F., Stief, Christian Georg, Tanagho, Emil A.   +3 more
core   +1 more source