Results 131 to 140 of about 251,076 (337)

Applying DanGer Shock Eligibility Criteria to a Real‐World Cohort of Cardiogenic Shock Patients

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The DanGer Shock trial investigated the effects of adding a microaxial flow pump to guideline‐recommended therapy in patients with ST‐elevation myocardial infarction (STEMI)‐related cardiogenic shock (CS), finding a lower all‐cause mortality at 180 days in the intervention group.
Raffaela Miriam Planka   +14 more
wiley   +1 more source

Prophylactic, manually titrable variable rate norepinephrine infusion for prevention of hypotension during spinal anesthesia for cesarean section: A randomized, double blind, controlled study

open access: yesJournal of Obstetric Anaesthesia and Critical Care
Background and Aims: Norepinephrine is recently being investigated for mitigation of spinal-induced hypotension. Our study aimed at evaluating the role of manually titrated infusion of norepinephrine in preventing hypotension in patients undergoing lower
Vikram Bedi   +5 more
doaj   +1 more source

Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

open access: yesChemistry–Methods, EarlyView.
The deuterated FMP‐10 analog, FMP‐10‐d3, enhances identification through isotopic labeling, providing structural insights via unique mass shifts. The approach improves the analysis of neurotransmitters and metabolites, facilitating neurochemical mapping and spatial metabolomics, with applications in neurodegenerative disease research. Mass spectrometry
Theodosia Vallianatou   +7 more
wiley   +1 more source

Opportunities and Challenges of the Application of Nuclear Magnetic Resonance‐Based Cerebrospinal Fluid Metabolomics for Clinical Research

open access: yesChemistry–Methods, EarlyView.
Cerebrospinal fluid (CSF) is an important diagnostic matrix in neurology. This review illustrates the potentials and pitfalls of current CSF analysis by nuclear magnetic resonance. Created with BioRender.com in BioRender. Berezhnoy, G. (2025) https://BioRender.com/x80l903. Web of Science is owned by Clarivate.
Georgy Berezhnoy   +4 more
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation as a potential therapy for attention deficit hyperactivity disorder: modulation of the noradrenergic pathway in the prefrontal lobe

open access: yesFrontiers in Neuroscience
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by developmental impairments, inattention, motor hyperactivity, and impulsivity. Currently, there is no effective intervention that can completely cure it. One
Jincao Zhi   +6 more
doaj   +1 more source

Generation of Pseudo Metabolites as a Side Reaction in On‐Tissue Chemical Derivatization in Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

open access: yesChemistry–Methods, EarlyView.
On‐tissue chemical derivatization reagents enhance sensitivity and specificity, but the impact of side reactions remains understudied. The reactive matrix FMP‐10 promotes Mukaiyama‐like condensation reactions between endogenous metabolites to form pseudo metabolites that are structurally identical to endogenous metabolites.
Tobias Bausbacher   +6 more
wiley   +1 more source

Hemodynamic Management with Vasopressin for Cardiovascular Surgery

open access: yesMedicina
Background and Objectives: Vasopressin increases blood pressure through aquaporin-2-mediated water retention and is useful for managing hemodynamics after surgery.
Hideyuki Kato   +5 more
doaj   +1 more source

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