Results 21 to 30 of about 101,853 (190)

Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]

, 2017
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M., Dhonnchadha, Brid A. Nic, Dwoskin, Linda P., Kantak, Kathleen M.   +3 more
core   +1 more source

Human norepinephrine metabolism [PDF]

Journal of Clinical Investigation, 1971
It has become increasingly apparent that evaluation of human norepinephrine metabolism simply by assay of catecholamines in urine is inadequate for differentiation of many physiological or pathological states. In an attempt to examine norepinepherine metabolism in the human subject, tritium-labeled d,l-norepinephrine was administered to 11 normal ...
Laura M. Bertani, Wilkek, Stanley E. Gitlow, Milton Mendlowitz, Sherwin Wilk   +4 more
openaire   +2 more sources

Structure Modeling of the Norepinephrine Transporter [PDF]

Biomolecules, 2020
The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases.
Izabella Góral, Kamil Łątka, Marek Bajda   +2 more
openaire   +4 more sources

Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs [PDF]

, 2019
Background High output subcutaneous nerve stimulation (ScNS) remodels the stellate ganglia and suppresses cardiac arrhythmia. Objective To test the hypothesis that long duration low output ScNS causes cardiac nerve sprouting, increases plasma ...
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Fishbein, Michael C., Grant, Maria B., Shen, Changyu, Wan, Juyi, Wang, Zhuo, Wong, Johnson, Yuan, Yuan   +10 more
core   +1 more source

Plasma norepinephrine and mortality [PDF]

Clinical Cardiology, 1995
Plasma norepinephrine levels, which reflect sympathetic nervous system activity, are almost universally elevated in patients with left ventricular dysfunction. This elevation occurs in patients with overt, symptomatic heart failure (HF) and in patients with asymptomatic left ventricular dysfunction.
openaire   +2 more sources

Mechanisms of hypertension during and after orthotopic liver transplantation in children [PDF]

, 1989
The aim of this study was to assess the hormonal alterations that may mediate the systemic hypertension that develops in patients during the perioperative period of orthotopic liver transplantation.
Akerstedt, Andrews, Ann Thompson, Arroyo, Bantle, Bantle, Baxter, Baylis, Bellet, Bernardi, Better, Bland, Bomzon, Bonjour, Borland, Busuttil, Cappuccio, Carlos Esquivel, Chrymko, Clement de Clety, Curtis, D. Ryan Cook, Demetrius Ellis, Epstein, Eskay, Filep, Floras, Gaillard, Gardner, Gartner, Gentile, Gerr, Glantz, Graystone, Henriksen, Hiatt, Januszewicz, Kimura, Kohno, Lau, Ledsome, Leslie, Loughran, Lustig, Mason, Minuk, Moss, Murrey, Nakai, Nicholls, Oaks, Ogawa, Palestine, Papadakis, Powell-Jackson, Ring-Larsen, Ring-Larsen, Rosanto, Salazar, Schacter, Seino, Shapiro, Skorecki, Starzl, Stephen Lawless, Task Force on Blood Pressure Control in Children, Thomas Starzl, Thompson, Vacanti, Voorhees, Weidle, Weidmann, Williams   +72 more
core   +1 more source

Preclinical discovery of duloxetine for the treatment of depression [PDF]

, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María, Elorza, Julián, Micó Segura, Juan Antonio, Perez-Caballero, Laura, Torres-Sanchez, Sonia   +4 more
core   +2 more sources

The Action of Norepinephrine, Epinephrine and Isopropyl Norepinephrine on the Rhythmic Function of the Heart [PDF]

Circulation, 1952
The actions of norepinephrine and isopropyl norepinephrine on the rhythmic property of the heart were studied and compared with that of epinephrine. Norepinephrine does not abolish cardiac standstill by carotid sinus stimulation, has no effect on the ventricular rate of heart block and induces a sinus bradycardia.
Morris H. Nathanson, Harold Miller
openaire   +3 more sources

Estimated central blood volume in cirrhosis [PDF]

, 1992
The estimated central blood volume (i.e., blood volume in the heart cavities, lungs and central arterial tree) was determined by multiplying cardiac output by circulatory mean transit time in 19 patients with cirrhosis and compared with sympathetic ...
Arendt, Arroyo, Bendtsen, Bichet, Bichet, Bonkovsky, Bosch, Campbell, Christensen, Epstein, Gerbes, Gerbes, Gerbes, Gerbes, Goetz, Gossmann, Groszmann, Henriksen, Henriksen, Henriksen, Henriksen, Henriksen, Henriksen, Keller, Kopp, Kostreva, Lassen, Liebermann, Nicholls, Panos, Rector, Rector, Ring-Larsen, Rodriguez-Roisin, Rowell, Sagawa, Salerno, Schlant, Schrier, Sherlock   +39 more
core   +1 more source

Serotonergic and Dopaminergic Function in Neuropsychiatrically Asymptomatic People With HIV on Antiretroviral Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau, Anna Lyndaker, Swati Shah, Paul Wakim, Amelia Mitchell, Cynthia Monroe, Alan Kim, Tracy L. Cropper, Govind Nair, Joseph Snow, Bryan R. Smith, Avindra Nath, Dima A. Hammoud   +12 more
wiley   +1 more source