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Autism Research, Volume 15, Issue 12, Page 2250-2264, December 2022., 2022 Abstract A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response [PDR] and event‐related potential [ERP]) indices may provide meaningful ...
Yesol Kim +3 more
wiley +1 more source
Journal of Intensive Care, 2018 Purpose It is not clear whether vasopressin versus norepinephrine changed mortality in clinical practice in the Vasopressin and Septic Shock Trial (VASST) coordinating center hospital after VASST was published.
James A. Russell +2 more
doaj +1 more source
Frontiers in Neurology, 2013 α2-adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion and modulates vascular tension.
Torill eBerg, Jørgen eJensen
doaj +1 more source
Biomolecules, 2020 Dementia and cognitive decline are global public health problems. Moderate consumption of alcoholic beverages reduces the risk of dementia and cognitive decline.
Tatsuhiro Ayabe +2 more
doaj +1 more source
Potential and Realized Impact of Astroglia Ca2 + Dynamics on Circuit Function and Behavior
Frontiers in Cellular Neuroscience, 2021 Astroglia display a wide range of spontaneous and behavioral state-dependent Ca2+ dynamics. During heightened vigilance, noradrenergic signaling leads to quasi-synchronous Ca2+ elevations encompassing soma and processes across the brain-wide astroglia ...
Eunice Y. Lim +4 more
doaj +1 more source
Structure Modeling of the Norepinephrine Transporter [PDF]
Biomolecules, 2020 The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases.
Izabella Góral +2 more
openaire +4 more sources
Human norepinephrine metabolism [PDF]
Journal of Clinical Investigation, 1971 It has become increasingly apparent that evaluation of human norepinephrine metabolism simply by assay of catecholamines in urine is inadequate for differentiation of many physiological or pathological states. In an attempt to examine norepinepherine metabolism in the human subject, tritium-labeled d,l-norepinephrine was administered to 11 normal ...
Laura M. Bertani +4 more
openaire +2 more sources
Journal of Neuroinflammation, 2010 Background Recent studies suggest an important role for neurotransmitters as modulators of inflammation. Neuroinflammatory mediators such as cytokines and molecules of the arachidonic acid pathway are generated and released by microglia.
Candelario-Jalil Eduardo +6 more
doaj +1 more source
Archives of Anesthesia and Critical Care, 2022 Background: Maternal hypotension due to spinal anaesthesia in caesarean section is commonly seen. Alongwith fluid loading, phenylephrine is used to manage the hypotension. However, this drug is associated with cardiovascular side effects.
Archita Patil +3 more
doaj +1 more source
Plasma norepinephrine and mortality [PDF]
Clinical Cardiology, 1995 Plasma norepinephrine levels, which reflect sympathetic nervous system activity, are almost universally elevated in patients with left ventricular dysfunction. This elevation occurs in patients with overt, symptomatic heart failure (HF) and in patients with asymptomatic left ventricular dysfunction.
openaire +2 more sources