Results 21 to 30 of about 242,932 (337)
Stress, norepinephrine and depression [PDF]
Acta Neuropsychiatrica, 2002 Experimental and clinical evidence implicates stress as a major predisposing factor in depression and other severe psychiatric disorders. In this review, evidence is presented to show how the impact of stress on the central sympathetic system leads to changes in the endocrine, immune and neurotransmitter axes which underlie the main clinical symptoms ...
openaire +3 more sources
How Is the Norepinephrine System Involved in the Antiepileptic Effects of Vagus Nerve Stimulation?
Frontiers in Neuroscience, 2021 Vagus Nerve Stimulation (VNS) is an adjunctive treatment for patients suffering from inoperable drug-resistant epilepsy. Although a complete understanding of the mediators involved in the antiepileptic effects of VNS and their complex interactions is ...
Alexandre Berger +11 more
doaj +1 more source
Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]
, 2018 Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
core +2 more sources
Journal of Intensive Care, 2018 Purpose It is not clear whether vasopressin versus norepinephrine changed mortality in clinical practice in the Vasopressin and Septic Shock Trial (VASST) coordinating center hospital after VASST was published.
James A. Russell +2 more
doaj +1 more source
The importance of norepinephrine in depression
Neuropsychiatric Disease and Treatment, 2011 Depression is one of the most common psychological diseases with significant potential morbidity and mortality. Although the underlying pathophysiology of depression has not been clearly defined, preclinical and clinical evidence suggest disturbances in serotonin (5-HT), norepinephrine (NE), and dopamine (DA) neurotransmission in the central nervous ...
Chantal Moret, Mike Briley
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Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]
, 2017 RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M. +3 more
core +1 more source
Frontiers in Neurology, 2013 α2-adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion and modulates vascular tension.
Torill eBerg, Jørgen eJensen
doaj +1 more source
Biomolecules, 2020 Dementia and cognitive decline are global public health problems. Moderate consumption of alcoholic beverages reduces the risk of dementia and cognitive decline.
Tatsuhiro Ayabe +2 more
doaj +1 more source
Potential and Realized Impact of Astroglia Ca2 + Dynamics on Circuit Function and Behavior
Frontiers in Cellular Neuroscience, 2021 Astroglia display a wide range of spontaneous and behavioral state-dependent Ca2+ dynamics. During heightened vigilance, noradrenergic signaling leads to quasi-synchronous Ca2+ elevations encompassing soma and processes across the brain-wide astroglia ...
Eunice Y. Lim +4 more
doaj +1 more source
Structure Modeling of the Norepinephrine Transporter [PDF]
Biomolecules, 2020 The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases.
Izabella Góral +2 more
openaire +4 more sources