Results 71 to 80 of about 101,853 (190)

Involvement of Noradrenergic Neurotransmission in the Stress- but not Cocaine-Induced Reinstatement of Extinguished Cocaine-Induced Conditioned Place Preference in Mice: Role for β-2 Adrenergic Receptors [PDF]

, 2010
The responsiveness of central noradrenergic systems to stressors and cocaine poses norepinephrine as a potential common mechanism through which drug re-exposure and stressful stimuli promote relapse.
A Dzung Lê, AD Le, AH Tiong, AM Snoddy, AN Fricks-Gleason, Andy Weyer, AR Davis, AS Kreibich, B Lee, B Ribeiro Do Couto, B Wang, C Drouin, C Lanteri, C Orsini, CA Jiménez-Rivera, CA Rudoy, Chad E Beyer, CJ McDougle, D Highfield, D Weinshenker, David A Baker, DJ Macey, DJ Sanger, DM Platt, ED Abercrombie, F Leri, FH Gawin, G Bricca, GC Harris, GC Harris, HD Schmidt, Holly Caretta, J Stewart, JC Winter, JM Dwyer, JM Finlay, John R Mantsch, JR Schank, KM Kampman, KM Kampman, L Cervo, L Lu, LJ Vanderschuren, M Sofuoglu, M Sofuoglu, M Sofuoglu, ME Reith, MH Baumann, MJ Millan, MK Horne, MS Kleven, MW Feltenstein, MY Li, OA Tjurmina, Oliver Vranjkovic, PJ Fletcher, R Sinha, R Sinha, R Sinha, RD Spealman, RE Bernardi, RE Bernardi, RJ Smith, RM Eglen, S Deyama, S Erb, S Erb, S Erb, S Wee, SM Florin, T Belej, T Tanaka, T Watanabe, TC Rainbow, TJ Beveridge, TM Tzschentke, VA Redila, WL Woolverton, X Wang, XY Zhang, XY Zhang, Y Itzhak, Y Shaham, Y Shaham, Y Shaham, Y Shaham, ZJ Brown   +86 more
core   +3 more sources

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

British Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan, Katherine Z. Isoardi, Darren M. Roberts, Ong Sook Har   +3 more
wiley   +1 more source

Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids. [PDF]

, 2019
Tramadol is one of the most commonly used analgesics worldwide, classified as having a low abuse potential by U.S. Drug Enforcement Agency, and often recommended in pain management guidelines.
Abagyan, Ruben, Atayee, Rabia S, Makunts, Tigran, U, Andrew   +3 more
core   +1 more source

Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]

, 2015
Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO, PUGLISI ALLEGRA, Stefano, VENTURA, Rossella   +2 more
core   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition

Chemistry &Biodiversity, EarlyView.
ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi, Hayder M. Al‐Kuraishy, Ali I. Al‐Gareeb, Ali K. Albuhadily, Morkoss M. Fakhry, Athanasios Alexiou, Marios Papadakis, Gaber El‐Saber Batiha   +7 more
wiley   +1 more source

Intramyocardial Hematoma After Percutaneous Coronary Intervention for Chronic Total Occlusion: Two Case Reports

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is an extremely challenging procedure, with intramyocardial hematoma (IMH) being one of its rare yet severe complications. In this report, we detail two cases of IMH occurring during PCI for CTO, emphasizing the importance of avoiding catheter pressure entrapment and ...
Xuefei Mu, Ziqi Li, Quanmin Jing, Yaling Han   +3 more
wiley   +1 more source

A Rare Case of Nitroglycerin Resistant Coronary Arterial Vasospasm During Coronary Artery Bypass Surgery

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery vasospasm following coronary artery bypass grafting (CABG) is a rare but potentially life‐threatening complication that can lead to myocardial ischemia, arrhythmias, and cardiogenic shock. Nitroglycerin‐resistant vasospasm, particularly involving the left main coronary artery (LMCA), poses significant diagnostic and ...
Dina Soliman, Cristian Castillo‐Rodriguez, Diego Cruz, John Abdelmalek   +3 more
wiley   +1 more source

Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals [PDF]

, 2019
Importance: Sepsis is present in many hospitalizations that culminate in death. The contribution of sepsis to these deaths, and the extent to which they are preventable, is unknown.
Anderson, Deverick J, Dantes, Raymund B, Epstein, Lauren, Hamad, Yasir, Jones, Travis M, Klompas, Michael, O\u27Brien, Cara, Pande, Anupam, Rhee, Chanu, Varon, Jack, Warren, David K   +10 more
core   +1 more source

The First‐in‐Man Technique of Drug Eluting and Perfusion Therapy for Left Main Coronary Artery Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Treating ostial left circumflex artery (LCx) lesions in percutaneous coronary intervention (PCI) for left main disease (LMD) remains a challenge. Despite recent recommendations for the use of drug‐coated balloon (DCB) in this lesion, there are concerns about crossover‐stenting from the left main trunk (LMT) to the left anterior ...
Takayuki Warisawa, Yoshiki Kawai, Takuya Matsumoto, Shingo Sato, Makoto Takeyama, Yuta Nakamura, Susumu Katsushika, Aritomo Katsura, Takahiro Sato, Masashiro Matsushita, Jiro Ando   +10 more
wiley   +1 more source