Results 71 to 80 of about 131,387 (308)
The role of norepinephrine in the pathophysiology of schizophrenia [PDF]
Neuroscience & Biobehavioral Reviews, 2019 Several lines of evidence suggest a role for norepinephrine (NE) in the pathophysiology of schizophrenia, and in pharmacological interventions. In the present paper, we review recent findings about the locus coeruleus-norepinephrine (LC-NE) system and its involvement in brain function and cognition to give a more integrated account of the possible role
Verónica Expósito de Mäki-Marttunen +2 more
openaire +3 more sources
Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering
Aggregate, EarlyView.Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang +3 more
wiley +1 more source
Toward molecular neuroeconomics of obesity [PDF]
arXiv, 2011 Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future study directions by unifying (i) economic theory of addiction and obesity (Becker and Murphy, 1988; Levy 2002 ...
arxiv
Separating Components of Attention and Surprise [PDF]
arXiv, 2016 Cognitive processes involved in both allocation of attention during decision making as well as surprise when making mistakes trigger release of the neurotransmitter norepinephrine, which has been shown to be correlated with an increase in pupil dilation, in turn reflecting raised levels of arousal.
arxiv
Animal Models and Experimental Medicine, EarlyView.Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani +6 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam +13 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin +9 more
wiley +1 more source
Alterations in microglial morphology concentrate in the habitual sleeping period of the mouse
Glia, Volume 71, Issue 2, Page 366-376, February 2023., 2023 Main Points We found regional differences of microglial morphology between the somatosensory cortex (SC), hippocampus (HC) and basal forebrain (BF). Cortical‐, but not HC‐ or BF microglial cell sizes negatively correlate with non‐REM sleep slow wave activity.
Sarah Katharina Steffens +2 more
wiley +1 more source
Norepinephrine mediates heart block during severe hypoglycemia in male rats
Physiological ReportsHypoglycemia is common in people with type 1 diabetes. Sometimes, severe hypoglycemia can be fatal. The underlying mechanisms by which severe hypoglycemia can lead to death are unclear. The sympathetic nervous system is thought to be proarrhythmic.
Emily H. Nuibe +2 more
doaj +1 more source