Results 71 to 80 of about 242,932 (337)
A cautionary note for researchers treating mice with the neurotransmitter norepinephrine
Biochemistry and Biophysics Reports, 2018 The sympathetic nervous system plays a crucial role in metabolic function and glucose homeostasis. Norepinephrine is the main neurotransmitter released from sympathetic neurons. The major goal of our studies was to examine the impact of norepinephrine on
Vance B. Matthews +2 more
doaj
The Gut Microbiota and Short-Chain Fatty Acids Profile in Postural Orthostatic Tachycardia Syndrome
Frontiers in Physiology, 2022 Postural orthostatic tachycardia syndrome (POTS) is a devastating chronic form of orthostatic intolerance associated with excessive heart rate increase without hypotension during upright posture. POTS patients exhibit increased circulating norepinephrine
Jeanne A. Ishimwe +5 more
doaj +1 more source
Chromosome movement in lysed mitotic cells is inhibited by vanadate. [PDF]
, 1978 Mitotic PtK1 cells, lysed at anaphase into a carbowax 20 M Brij 58 solution, continue to move chromosomes toward the spindle poles and to move the spindle poles apart at 50% in vivo rates for 10 min.
CANDE, W. Zacheus, Wolniak, S
core +1 more source
Computer-assisted ex vivo, normothermic small bowel perfusion [PDF]
, 2000 Background: In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena.
Eder, M. +6 more
core +1 more source
The role of norepinephrine in the pathophysiology of schizophrenia [PDF]
Neuroscience & Biobehavioral Reviews, 2019 Several lines of evidence suggest a role for norepinephrine (NE) in the pathophysiology of schizophrenia, and in pharmacological interventions. In the present paper, we review recent findings about the locus coeruleus-norepinephrine (LC-NE) system and its involvement in brain function and cognition to give a more integrated account of the possible role
Verónica Expósito de Mäki-Marttunen +2 more
openaire +3 more sources
Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury
Advanced Science, EarlyView.Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley +1 more source
Insights on neuroendocrine regulation of immune mediators in female reproductive aging and cancer
AIMS Molecular Science, 2021 Neuroendocrine-immune homeostasis in health and disease is a tightly regulated bidirectional network that influences predisposition, onset and progression of age-associated disorders. The complexity of interactions among the nervous, endocrine and immune
Hannah P. Priyanka +4 more
doaj +1 more source
PET Imaging of Norepinephrine Transporters [PDF]
Current Pharmaceutical Design, 2006 The involvement of the norepinephrine transporter (NET) in the pathophysiology and treatment of attention deficit hyperactivity disorder (ADHD), substance abuse, neurodegenerative disorders (e.g., Alzheimer's disease (AD) and Parkinson's disease (PD)) and depression has long been recognized.
Yu-Shin Ding, Jean Logan, Kuo-Shyan Lin
openaire +4 more sources
Advances in Medical Devices for Augmented Acupuncture Therapy
Advanced Science, EarlyView.Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai +7 more
wiley +1 more source
SPLICEIT Fluorescent Sensor for Integrating Dopamine Release with Cellular Resolution
Angewandte Chemie, EarlyView.“Single‐chain protein‐based ligand indication through a chimerically‐engineered integrator tool” (SPLICEIT) is a G‐protein coupled receptor‐based sensor design that leaves a permanent fluorescent mark. We show dopamine detection in primary cultured neurons with a fourfold signal increase normalized to an mCherry (mCh) marker.
Steven M. Havens +7 more
wiley +2 more sources