Results 61 to 70 of about 5,761 (235)

S3 Guideline for the treatment of psoriasis vulgaris, adapted from EuroGuiDerm – part 1: Treatment recommendations and monitoring

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 1, Page 122-137, January 2026.
Summary This first part of the updated German S3 guideline on the treatment of psoriasis vulgaris covers the sections on treatment recommendations, treatment goals, and monitoring of therapies. The recommendations are based on the current Cochrane network meta‐analysis, the results of which are also summarized.
Alexander Nast   +25 more
wiley   +1 more source

Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans [PDF]

open access: yes, 2014
Oral contraceptive (OC) use is associated with increased intra-renal renin-angiotensin-aldosterone system (RAA System) activity and risk of nephropathy, though the contribution of progestins contained in the OC in the regulation of angiotensin-dependent ...
Ahmed, Sofia B.   +3 more
core   +1 more source

Round Table Discussion: Aesthetic Treatment Considerations for the Perimenopausal & Menopausal Patient

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Menopause is a normal feature of the female aging process that commonly occurs during the 6th decade of life. During perimenopause, many negative effects begin to occur affecting the skin that are associated with decreasing production of estrogen, progesterone, and testosterone.
Sabrina G. Fabi   +4 more
wiley   +1 more source

New approaches for estimating risk from exposure to diethylstilbestrol. [PDF]

open access: yes, 1999
A subgroup from a National Institute of Environmental Health Sciences, workshop concerned with characterizing the effects of endocrine disruptors on human health at environmental exposure levels considered the question, If diethylstilbestrol (DES) were ...
Cunha, GR   +7 more
core   +2 more sources

Uterine “twisting sign”: A new potential ultrasonographic soft marker for deep endometriosis

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 1355-1363, December 2025.
Abstract Objective The objective of the current study was to evaluate the “twisting sign,” defined as uterine fundus rotation observed on transvaginal sonography (TVS), as a potential soft marker for deep endometriosis (DE) and its association with specific DE localizations and indirect signs.
Fabio Barra   +7 more
wiley   +1 more source

The progestin levonorgestrel affects sex differentiation in zebrafish at environmentally relevant concentrations [PDF]

open access: yes, 2015
Synthetic progestins have become widespread environmental contaminants and may cause adverse effects on fish. In the present study, we investigated the effects of levonorgestrel (LNG) on sex differentiation in zebrafish (Danio rerio).
Guo, Yongyong   +3 more
core   +1 more source

Tanshinone-I for the treatment of uterine fibroids: Molecular docking, simulation, and density functional theory investigations

open access: yesSaudi Pharmaceutical Journal, 2023
Uterine fibroids (UF), most prevalent gynecological disorder, require surgery when symptomatic. It is estimated that between 25 and 35 percent of women wait until the symptoms have worsened like extended heavy menstrual bleeding and severe pelvic pain ...
Abhishek Tiwari   +12 more
doaj   +1 more source

Establishing a Quantitative Framework for Combined Oral Contraceptives: Evaluating the Impact of Drug–Drug Interactions on Exposure and Clinical (Surrogate) Efficacy Endpoints

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1855-1863, December 2025.
Abstract According to the FDA Guidance for Industry on Clinical Drug Interaction (DDI) Studies with Combined Oral Contraceptives (COCs), sponsors are expected to conduct dedicated clinical DDI studies if in vitro findings suggest weak or moderate CYP3A induction, while concomitant use of COCs with strong inducers should be avoided. The guidance further
Dain Chun   +7 more
wiley   +1 more source

Efficacy of hormonal therapies for decreasing uterine volume in patients with adenomyosis

open access: yesGynecology and Minimally Invasive Therapy, 2018
Study objective: The aim of this study is to evaluate the efficacy of hormonal therapies for inhibiting an increase in uterine volume in patients with adenomyosis. Design: This was retrospective cohort study.
Takashi Matsushima   +4 more
doaj   +1 more source

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