Results 51 to 60 of about 3,314 (195)

Effect of Protease Inhibitors on Steady-State Pharmacokinetics of Oral Norethindrone Contraception in HIV-Infected Women [PDF]

OBJECTIVE: Pharmacokinetic interactions exist between combined oral contraceptives and protease inhibitors (PI). However, such information is lacking for progestin-only oral contraception.
Kovacs, Andrea, Atrio, Jessica, Stanczyk, Frank Z., Cherala, Ganesh, Mishell, Daniel R., Jr., Neely, Michael   +5 more
core   +6 more sources

Progestin Pollution in Surface Waters of a Major Southwestern European Estuary: The Douro River Estuary (Iberian Peninsula)

Toxics
The concentrations and spreading of eight synthetic and two natural progestins (PGs) were investigated in surface waters from ten sites at the Douro River Estuary.
Frederico Silva, Rodrigo F. Alves, Eduardo Rocha, Maria João Rocha   +3 more
doaj   +1 more source

Compound Library Screening Identified Cladribine as a Novel Radiosensitizer for Prostate Cancer

Cancer Science, Volume 117, Issue 4, Page 1136-1147, April 2026.
The combination of cladribine and irradiation significantly suppressed the growth of DU145‐derived tumors compared with the DMSO plus irradiation group in the mouse model. In addition, it also elevated the percentage of γH2AX‐positive cells after irradiation.
Toshiki Oka, Koji Hatano, Shohei Katsuki, Tomohiro Kanaki, Shunsuke Inoguchi, Masaru Tani, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Keisuke Tamari, Bangzhong Lin, Akiyoshi Tani, Kazutake Tsujikawa, Yutaka Takahashi, Kazuhiko Ogawa, Shawn E. Lupold, Norio Nonomura   +26 more
wiley   +1 more source

Amino Acid Esters of Norethindrone as Possible Acrosin Inhibitors

, 1986
Medicinal Chemistry Division, Central Drug Research Institute, Lucknow-226 001 Manuscript received 10 October 1985, accepted 17 February 1986 A series of amino acid esters of norethindrone (I) have been synthesised as possible acrosin inhibitors by ...
KASTURl LAL, PANNA LAL KOLEY, SUPRABHAT RAY   +2 more
core   +1 more source

Are saliva and bile sources of oxalate secretion into the human gastrointestinal tract?

Physiological Reports, Volume 14, Issue 8, April 2026.
Abstract Elevated urine oxalate (hyperoxaluria) is a risk factor for kidney stones. Normally eliminated by the kidneys, oxalate originates from endogenous metabolism and dietary absorption but secretion into the intestine remains an open question. We considered saliva and bile as two potential sources.
Emma Earhart, Thomas Tielleman, John Knight, Jonathan M. Whittamore   +3 more
wiley   +1 more source

Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts

Physiological Reports, Volume 14, Issue 8, April 2026.
The effect of oral contraceptives (OCs) on muscle repair is unknown. Using electrical pulse stimulation to simulate damage in C2C12 myoblasts treated with four OC generations (MPA, LNG, DSG, DRP combined with ethinyl estradiol), we assessed proliferation, differentiation, migration, creatine kinase, myogenic proteins, and hormone receptor protein ...
Mai Wageh, Michael Kamal, Gianni Parise
wiley   +1 more source

Efficacy of hormonal therapies for decreasing uterine volume in patients with adenomyosis

Gynecology and Minimally Invasive Therapy, 2018
Study objective: The aim of this study is to evaluate the efficacy of hormonal therapies for inhibiting an increase in uterine volume in patients with adenomyosis. Design: This was retrospective cohort study.
Takashi Matsushima, Shigeo Akira, Takehiko Fukami, Koichi Yoneyama, Toshiyuki Takeshita   +4 more
doaj   +1 more source

Effects of oral, continuous and transdermal cyclic 17-? estradiol and norethindrone acetate replacement therapy on platelet aggregation in postmenopausal women

, 2002
OBJECTIVE: To evaluate the affects of an oral continuous and transdermal cyclic 17-beta estradiol and norethindrone acetate combination on platelet aggregation in postmenopausal women.
Yüce, MA, Yardim, T, Kaplan, PB, Sayin, NC, Gücer, F   +4 more
core   +3 more sources

Intertidal Warfare: Synergistic Allelopathy Mediates Spatial Competition between Two Marine Calcareous‐Shelled Sessile Organisms

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li, Zixin Huo, Shanshan Yao, Xianmeng Liang, Yiran Zhao, Yanxin Wang, Shifeng Guo, Caihuan Ke, Pei Su, Danqing Feng   +9 more
wiley   +1 more source

Combined Continuous Ethinyl Estradiol/Norethindrone Acetate Does Not Improve Forearm Blood Flow in Postmenopausal Women at Risk for Cardiovascular Events: A Pilot Study [PDF]

, 2007
Objective: This study sought to determine whether combined continuous ethinyl estradiol and norethindrone acetate, a postmenopausal hormone therapy (HT) combination designed to have fewer side effects than cyclical therapies and therapies using ...
Rose, Patricia A., Brook, Robert D., Kehrer, Christine, Duvernoy, Claire S., Kim, H. Myra   +4 more
core   +1 more source