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Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis

open access: yesEuropean Journal of Obstetrics, Gynecology and Reproductive Biology, 2017
To study the efficacy of long-term treatment with norethindrone acetate (NETA) in patients with rectovaginal endometriosis.This retrospective cohort study included 103 women with pain symptoms caused by rectovaginal endometriosis. Patients received NETA alone (2.5mg/day up to 5mg/day) for 5 years.
Matteo Morotti   +2 more
exaly   +5 more sources
Some of the next articles are maybe not open access.

Use of Norethindrone Acetate Alone for Postoperative Suppression of Endometriosis Symptoms

Journal of Pediatric and Adolescent Gynecology, 2012
To evaluate the efficacy and tolerability of norethindrone acetate (NA) as single-agent hormonal therapy for suppression of endometriosis symptoms in adolescents and young adults.Retrospective study.Two academic medical centers.A keyword search using the query 'NA' was applied to the electronic medical records of all women treated by one gynecologist ...
D J Käser, S A Missmer, M R Laufer
exaly   +3 more sources

Bioavailability of norethindrone in women and rabbits after administration of norethindrone acetate through the subcutaneous route

Experientia, 1982
The levels of available norethindrone were found to be similar in women and rabbits after s.c. administration of crystalline and amorphous, norethindrone acetate respectively, and this study indicates that the rabbit may be used as an animal model for further investigation with this contraceptive steroid.
K R Laumas, V Hingorani
exaly   +2 more sources

Norethindrone acetate inhibition of triglyceride synthesis and release by rat hepatocytes

Atherosclerosis, 1983
The progestin, norethindrone acetate has been widely administered to patients in the form of oral contraceptives; however, its hypolipemic action has received little study. This report describes the effects of conventional doses of norethindrone acetate (100 micrograms/day.kg body weight 0.75) on rat plasma lipid levels in vivo as well as the mechanism
B M Wolfe
exaly   +3 more sources

Absorption of Chlormadinone Acetate and Norethindrone from In Situ Rat Gut

Journal of Pharmaceutical Sciences, 1973
The GI absorption of chlormadinone acetate and norethindrone was studied in a rat in situ preparation. The data evaluated with respect to the absorption half-life in the ligated stomach and intestine suggest that chlormadinone acetate is absorbed slightly more rapidly than norethindrone and that both steroids are absorbed to a greater extent in the ...
exaly   +3 more sources

Pharmacokinetics of norethindrone acetate in women

American Journal of Obstetrics and Gynecology, 1979
The plasma half-life, MCR and plasma metabolite levels at various time intervals have been studied in six women after an intravenous injection of 3H-norethindrone acetate. The disappearance curve due to norethindrone acetate showed an initial rapid disappearance of 3H with an average half-life of 7.5 minutes and a subsequent slow disapperance with a ...
H, Singh   +6 more
openaire   +2 more sources

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