Results 31 to 40 of about 3,314 (195)

The influence of norethindrone and mestranol on pituitary–adrenal function

open access: yes, 1968
Female Wistar rats were force-fed either Ortho-Novum (66 μg norethindrone and 1 μg mestranol), norethindrone (66 μg), mestranol (1 μg), or water daily for 1 month.
David R. Usher
core   +1 more source

Pharmacokinetic and Drug–Drug Interaction Profiles of the Combination of Tezacaftor/Ivacaftor

open access: yesClinical and Translational Science, 2019
Drug–drug interaction (DDI) studies are described for tezacaftor/ivacaftor, a new cystic fibrosis transmembrane conductance regulator modulator therapy for the treatment of cystic fibrosis.
Varun Garg   +11 more
doaj   +1 more source

Graphene Oxide Membrane Immobilized Aptamer as a Highly Selective Hormone Removal

open access: yesMembranes, 2020
Three-dimensional (3D) reduced graphene oxide (rGO) modified by polyethyleneimine (PEI) was prepared and functionalized by fluorophore-labeled dexamethasone-aptamer (Flu-DEX-apt) via π–π stacking interaction.
Siham Chergui   +3 more
doaj   +1 more source

Effect of Zhuyun I Recipe Capsule Enema on the Immune Microenvironment of the Endometrium during Implantation Window in Rats

open access: yesEmergency Medicine International, 2022
Background. Preterm birth is the leading cause of neonatal death, and there are no effective clinical means for the prevention and treatment of spontaneous preterm birth, mainly because the mechanism for labor initiation has not been fully elucidated ...
Hang Zhou   +11 more
doaj   +1 more source

Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis : a before and after study

open access: yes, 2016
OBJECTIVE: To assess the proportion of patients satisfied with their treatment before and after a systematic change from norethindrone acetate to dienogest as the first-line progestin for symptomatic endometriosis.
B. Bracco   +6 more
core   +1 more source

Membranous dysmenorrhea and decidual casts: A scoping review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Membranous dysmenorrhea, characterized by the expulsion of intact endometrial tissue rather than gradual dissolution during menstruation, occasionally presents as a decidual cast—a complete triangular mold of the uterine cavity. This poorly understood condition is likely underdiagnosed.
Lovisa Brehmer, Hedvig Engberg
wiley   +1 more source

Some characteristics of the uterine progestorone receptor and the effects of norethindrone on conception in the rock hyrax (Procavia capensis) [PDF]

open access: yes, 2006
Dissertation (MSc (Zoology))--University of Pretoria, 2006.The mean dissociation constant (± SEM) of the uterine progesterone receptor for progesterone in eight rock hyraxes, culled at Elandsrand Mine Reserve, was 1.78 nM (±O.l07).

core   +1 more source

Effect of Elagolix Exposure on Clinical Efficacy End Points in Phase III Trials in Women With Endometriosis‐Associated Pain: An Application of Markov Model

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2020
Elagolix is an oral gonadotropin‐releasing hormone antagonist approved by the US Food and Drug Administration (FDA) for the management of moderate‐to‐severe pain associated with endometriosis and in combination with estradiol/norethindrone acetate ...
Insa Winzenborg   +5 more
doaj   +1 more source

Integrating transcriptomics and network analysis-based multiplexed drug repurposing to screen drug candidates for M2 macrophage-associated castration-resistant prostate cancer bone metastases

open access: yesFrontiers in Immunology, 2022
Metastatic castration-resistant prostate cancer (CRPC) has long been considered to be associated with patient mortality. Among metastatic organs, bone is the most common metastatic site, with more than 90% of advanced patients developing bone metastases (
Jinyuan Chang   +6 more
doaj   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas   +3 more
wiley   +1 more source

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