Results 81 to 90 of about 1,322 (181)
Serum concentrations of fluoxetine in the clinical treatment setting
, 2001 This article discusses fluoxetine serum concentrations as displayed in a clinical setting. A racemic serum fluoxetine and norfluoxetine high-performance liquid chromatography method, including ultraviolet light detection, was used for routine therapeutic
Reis, Margareta, +2 more
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, 2003 A simple and innovative assay is described which allows the chiral separation of the four enantiomers of fluoxetine and norfluoxetine, with performance characteristics adequate for therapeutic drug monitoring.
SCORDO G. +7 more
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, 2013 Background Drug-induced long QT syndrome is generally ascribed to inhibition of the cardiac rapid delayed rectifier potassium current (I-Kr). Effects on the slow delayed rectifier potassium current (I-Ks) are less recognized.
Veerman, Christiaan C. +9 more
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, 1996 The principal goal of this work was to investigate the liquid chromatographic retention behaviour of fluoxetine and norfluoxetine using HPLC with respect to mobile phase composition, pH, flow rate and the amount of the native β-cyclodextrin (β-CD) or the
Parissi-Poulou, M., Piperaki, S.
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, 2009 A sensitive, selective, and reproducible in-tube polypyrrole-coated capillary (PPY) solid-phase microextraction and liquid chromatographic method for fluoxetine and norfluoxetine enantiomers analysis in plasma samples has been developed, validated, and ...
SILVA, Bruno Jose Goncalves +2 more
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, 2005 A selective, sensitive, and precise HPLC method for the simultaneous determination of fluoxetine (FL) and its N-demethylated metabolite norfluoxetine (NFL) in human plasma has been developed.
Ersoy, L +4 more
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, 2004 Fluoxetine (d,l-N-methyl-3-phenyl-3-[(alpha,alpha,alpha,-trifluoro-p-tolyl)oxy]propyl-amine) is the parent drug of the SSRI (selective serotonin reuptake inhibitor) antidepressant class.
F. Bugamelli +5 more
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Enantioselective determination of fluoxetine and norfluoxetine in wastewater by HPLC-FD using SPE [PDF]
, 2013 Microbial degradation of chiral compounds during wastewater treatment processes can be enantioselective and needs chiral analytical methodology to discriminate the biodegradation of both enantiomers.
Moreira, Irina S. +5 more
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, 2001 The formation of R-and S-norfluoxetine was analyzed in vitro in human liver microsomes. Low apparent K m values for R-norfluoxetine formation of Յ8 M and S-norfluoxetine of Ͻ0.2 M were determined.
Mark Vandenbranden +5 more
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, 2005 A selective, sensitive, simple, and rapid method for the simultaneous determination of fluoxetine (FL) and norfluoxetine (nor-FL) was developed and validated, and further applied to analyze plasma samples obtained from FL-treated patients with Parkinson ...
Kovacević, I +4 more
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