Results 11 to 20 of about 3,430 (196)

Questions in self‐selection studies used in consumer research for nonprescription drug candidates: Limitations and recommendations

Clinical and Translational Science
Self‐selection studies assess participants' ability to use label information to decide if a proposed nonprescription drug is appropriate for their use. The optimal use of information from participants' responses in these trials has not been studied. Data
Eric P. Brass, Russell D. Bradford, Arthur Stone   +2 more
doaj   +2 more sources

Development of breakthrough bleeding model of combined-oral contraceptives utilizing model-based meta-analysis. [PDF]

CPT Pharmacometrics Syst Pharmacol
Abstract Breakthrough bleeding (BTB) is a common side effect of hormonal contraception and is thought to impact adherence to combined oral contraceptives (COCs) but respective dose–response relationships are not yet fully understood. Therefore, the objective of this model‐based meta‐analysis (MBMA) was to establish dose–response for COCs containing ...
Chen H, Chun D, Lingineni K, Guzy S, Cristofoletti R, Hoechel J, Jiao T, Cicali B, Vozmediano V, Schmidt S.   +9 more
europepmc   +2 more sources

Estudio clínico comparativo de dos diferentes progestágenos administrados en implantes subdérmicos

Ciencia y Sociedad, 1978
Este estudio muestra que las cápsulas de silastic contienen dos progestágenos diferentes, etil-norges-trienona y d-norgestrel, fueron colocadas en la región ventral del brazo subdominante de 100 mujeres, para fines anticonceptivos, en un estudio doble ...
Francisco Álvarez Sánchez, Víctor M. Montes de Oca, Vivian Brache de Mejía, Aníbal Faundes   +3 more
doaj   +1 more source

A case report and literature review: A 19-year-old with endometrial carcinoma treated with medroxyprogesterone acetate. Importance of the medical interview and endometrial examination. [PDF]

Clin Case Rep
Key Clinical Message A 19‐year‐old woman had stage IA endometrial carcinoma treated with medroxyprogesterone acetate and experienced a recurrence. This patient's experience illustrates the importance of a thorough history and endometrial assessment in younger patients.
Katsuma S, Ariyoshi K, Nio A, Taguchi K, Sonoda K.   +4 more
europepmc   +2 more sources

Experiences of progestin‐only pill users in the United States and attitudes toward over‐the‐counter access

Perspectives on Sexual and Reproductive Health, Volume 55, Issue 2, Page 104-112, June 2023., 2023
Abstract Context Removing the prescription requirement and making oral contraceptive pills available over the counter (OTC) could increase contraceptive access in the United States. Despite current efforts to make a progestin‐only pill (POP) available OTC, there are no qualitative data exploring the experiences of POP users and their perspectives on ...
Carmela Zuniga, Hannah Forsberg, Kate Grindlay   +2 more
wiley   +1 more source

Monitoring Drug Safety Information - Recommendations of Foreign Regulatory Authorities

Безопасность и риск фармакотерапии, 2020
Analysis of administrative decisions of foreign regulatory authorities on the recoil of medicines and/or the need for changes in the instructions for their medical use due to changes in the safety profi le, conducted by experts of the Scientifi c Centre ...
Elena V. Shubnikova, Marya A. Darmostukova, Irina I. Snegireva, Evgeniya O. Zhuravleva   +3 more
doaj   +1 more source

Facile, Single‐Step Synthesis of a Series of D‐Ring Ethisterones Substituted with 1,4‐1,2,3‐Triazoles: Preliminary Evaluation of Cytotoxic Activities

ChemMedChem, Volume 18, Issue 8, April 17, 2023., 2023
Facile single‐step syntheses of a series of D‐ring ethisterones substituted with 1,4‐1,2,3‐triazoles were conducted. Preliminary evaluation of their cytotoxic activities against human cancer cell lines has revealed promising cytotoxicities. For instance, activities against leukemia, lung cancer, and cancer‐type cells were observed for two of these ...
Daniel Canseco‐González, Isaac Rodríguez‐Victoria, Teresa Apan‐Ramírez, Alejandro O. Viviano‐Posadas, Juan S. Serrano‐García, Antonino Arenaza‐Corona, Adrian L. Orjuela, Jorge Alí‐Torres, Alejandro Dorazco‐González, David Morales‐Morales   +9 more
wiley   +1 more source

Divergent effects of d-norgestrel on the metabolism of rat very low density and low density apolipoprotein B.

Journal of Lipid Research, 1988
Rats treated with the contraceptive steroid d-norgestrel have lower plasma very low density lipoprotein (VLDL)-triglycerides and higher low density lipoprotein (LDL)-cholesterol than controls.
R Khokha, M W Huff, B M Wolfe
doaj   +1 more source

Administración continua de 30 Microgramos de d-Norgestrel como Anticonceptivo en 349 mujeres durante 4.481 Ciclos.

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018
1) Se presenta un informe sobre el uso de d-Norgestel en microdosis de 30 micogramos diarios con administración continua, como anticonceptivo en 349 pacientes con un total de 4.481 ciclos/mujer en un grupo socio-económicamente bajo.
Guillermo López-Escobar, Hugo Willomitzer, Jaime Ramírez Sánchez, José D. Castillo   +3 more
doaj   +1 more source

Estudio Endometrial en la Administración continua de Microdosis de 30 Microgramos de d-Norgestrel

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018
Se presentaron los resultados de un estudio hecho sobre un total de 171 biopsias endometriales tomadas en 61 pacientes que estaban recibiendo tratamiento anticonceptivo con microdosis de 30 microgramos de d-Norgestrel en administración continua. 
Ricardo Alvarado, Guillermo López-Escobar, Hugo Willomitzer, José D. Castillo   +3 more
doaj   +1 more source