Results 111 to 120 of about 16,014,283 (355)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

UA95/1 Special Announcement of Glasgow Normal School [PDF]

open access: yes, 1880
Brochure created by the Glasgow Normal School to advertise services and recruit students. Includes sections on the history of the school, curriculum, literary societies, social features, boarding homes, tuition and ...
Glasgow Normal School
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Nomogram predicting macroscopic finding with limited or no clinical implication in 19175 patients referred to esophagogastroduodenoscopy

open access: yesCogent Medicine, 2016
Objective: The diagnostic yield of esophagogastroduodenoscopy (EGD) depends on appropriate patient selection. The aim of the current study was to create a nomogram predicting findings with limited or no clinical implication in patients referred to EGD ...
Bo Bendvold   +4 more
doaj   +1 more source

Body Fat Percentage in Relation to Lung Function in Individuals with Normal Weight Obesity [PDF]

open access: gold, 2019
Yuan‐Yuei Chen   +8 more
openalex   +1 more source

UA95/3 Commencement Program [PDF]

open access: yes, 1880
Commencement program for the Scientific Class of 1880, graduates are listed along with their home ...
Glasgow Normal School
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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