Results 111 to 120 of about 9,879,737 (342)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Outer measures and associated lattice properties

International Journal of Mathematics and Mathematical Sciences, 1993
Zero-one measure characterizations of lattice properties such as normality are extended to more general measures. For a given measure, we consider two associated “outer” measures and attempt to obtain the “outer”-measurable sets.
Peter M. Grassi
doaj   +1 more source

Perturbation of Normal Operators [PDF]

, 1954
S. L. Jamison
openalex   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Topological properties of spaces ordered by preferences

International Journal of Mathematics and Mathematical Sciences, 1999
In this paper, we analyze the main topological properties of a relevant class of topologies associated with spaces ordered by preferences (asymmetric, negatively transitive binary relations).
J. C. R. Alcantud
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Measure characterizations and properties of normal and regular lattices

International Journal of Mathematics and Mathematical Sciences, 1991
Various equivalent characterizations of normality are considered and a measure theoretic definition is given for strongly normal lattices. Measure conditions related to the apace of σ-smooth, lattice-regular, 0−1 measures are noted which imply, or are ...
Peter M. Grassi
doaj   +1 more source

ANALYSIS OF THE BLOOD SUGAR RESPONSE OF OBESE-HYPERGLYCEMIC MICE AND NORMAL MICE TO HORMONES: INSULIN, GLUCAGON, AND EPINEPHRINE1 [PDF]

, 1956
Kenneth H. Shull, Jean Mayer, Demetra J. Silides   +2 more
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

ANTROPOLOGÍA Y ALTERIDAD. DE LA NATURALEZA HUMANA A LA NORMALIDAD SOCIAL

Daimon, 1996
La Antropología, en cuanto «ciencia de la cultura», nace como mirada hacia el otro. La composición de esta mirada está sostenida por la nueva distribución que hace el pensamiento europeo de sus propios espacios de lo normal y lo patológico.
José Lorite Mena
doaj