Results 11 to 20 of about 3,804,201 (207)
Aging Pathobiology and Therapeutics, 2022 The descriptive term “normal” aging is often used in scientific literature to indicate commonly occurring changes with increasing age in the absence of overt disease. However, significant molecular and geropathological changes are increasingly present to indicate there is nothing normal about aging.
Chloe, Johnson, Warren, Ladiges
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Sleep Medicine Clinics, 2018 Sleep is a key determinant of healthy and cognitive aging. Sleep patterns change with aging, independent of other factors, and include advanced sleep timing, shortened nocturnal sleep duration, increased frequency of daytime naps, increased number of nocturnal awakenings and time spent awake during the night, and decreased slow-wave sleep.
Junxin, Li +2 more
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Science for the Post-Normal Age [PDF]
Commonplace, 1993 In response to the challenges of policy issues of risk and the environment, a new type of science-‘post-normal’-is emerging. This is analysed in contrast to traditional problem-solving strategies, including core science, applied science, and professional consultancy.
Funtowicz, S., Ravetz, J. R.
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European Journal of Orthodontics, 2018 The aim of this study was to evaluate the qualitative occlusal changes in individuals with normal occlusion during a period of 47 years.The sample comprised dental models of 20 subjects with normal occlusion (8 males; 12 females) taken at 13.2 years (T1) and 60.9 years of age (T2). The occlusal features were evaluated with the objective grading system (
Felicia Miranda +6 more
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Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy
Journal of Immunology Research, 2019 Bispecific antibodies (BsAbs) are a sort of dual functional proteins with specific binding to two distinct targets, which have become a focus of interest in antibody engineering and drug development research and have a promising future for wide ...
Shixue Chen +5 more
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Frontiers in Neuroscience, 2020 Quantitative MRI modalities, such as diffusion tensor imaging (DTI) or magnetization transfer imaging (MTI) are sensitive to the neuronal effects of aging of the cerebral white matter (WM), but lack the specificity for myelin content.
Tobias D. Faizy +16 more
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Frontiers in Aging Neuroscience, 2020 The aging of the brain is a well-investigated topic, but existing analyses have mainly focused on Caucasian samples. To investigate brain aging in East Asians, we measured cortical and subcortical volumes from magnetic resonance imaging (MRI) scans of 1 ...
Yu Yong Choi +16 more
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Frontiers in Physiology, 2018 The hippocampus plays an important role in memory function relying on information interaction between distributed brain areas. The hippocampus can be divided into the anterior and posterior sections with different structure and function along its long ...
Xinwei Li +9 more
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Frontiers in Aging Neuroscience, 2020 Reduced pain tolerance may be one of the possible explanations for high prevalence of chronic pain among older people. We hypothesized that age-related alterations in pain tolerance are associated with functioning deterioration of the frontal cortex ...
Shu Zhou +7 more
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Frontiers in Psychiatry, 2021 Background: Apathy has been suggested as a potential predictor of mild cognitive impairment (MCI) progression to dementia. Whether it might predict the transition from normal cognitive function to cognitive impairment has been less studied.
Zili Fan +18 more
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