Results 71 to 80 of about 1,176,227 (289)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Large deviations for weighted random sums
Nonlinear Analysis, 2013 In the present paper we consider weighted random sums ZN = ∑j=1 N ajXj, where 0 0. Throughout this paper N is independent of {X, Xj , j = 1, 2,...} and, for definiteness, it is assumed Z0 = 0. The main idea of the paper is to present results on theorems
Aurelija Kasparavičiūtė +1 more
doaj
Multivariate approximation in total variation, II: Discrete normal approximation
The Annals of Probability, 2018 arXiv:1512.07400 has been split into two parts: this is Part ...
Barbour, A. D., Luczak, M. J., Xia, A.
openaire +6 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Approximations to distribution of median in stratified samples
Lietuvos Matematikos Rinkinys, 2011 We consider an Edgeworth type approximation to the distribution function of sample median in the case of stratified samples drawn without replacement. We give explicit expression of this approximation, and also its empirical version based on bootstrap ...
Andrius Čiginas, Tomas Rudys
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Skew-Normal Posterior Approximations
, 2023 Many approximate Bayesian inference methods assume a particular parametric form for approximating the posterior distribution. A multivariate Gaussian distribution provides a convenient density for such approaches; examples include the Laplace, penalized quasi-likelihood, Gaussian variational, and expectation propagation methods.
Zhou, Jackson +2 more
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
A Closed-Form Cubic–Logistic Approximation to the Normal Cumulative Distribution Function
MathematicsAccurate evaluation of the standard normal cumulative distribution function is fundamental in many areas of mathematics, statistics, and applied computation, yet no closed-form expression in elementary functions exists.
Michael Arnold Frölich
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Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source