Results 231 to 240 of about 1,713,760 (284)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Genomic landscape of radiation-induced somatic mutations in a normal cell. [PDF]

Carcinogenesis
Matsuda Y, Tanabe O.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Somatic and germline mutational processes across the tree of life

Campbell P, Lee S, Wang Y, Haynes H, Mitchell E, Maddison M, Crowley L, Adkins P, Mieszkowska N, Blaxter M, Durbin R.   +10 more
europepmc   +1 more source

Differentially expressed genes in rabbits with traumatic proliferative vitreoretinopathy based on high-throughput sequencing. [PDF]

Int J Ophthalmol
Tang YJ, Liu JY, Zhang SX, Liu BY, Quan L, Xu QH.   +5 more
europepmc   +1 more source

Encephalitis-like presentation of methylmalonic acidemia with homocystinuria in a postpartum woman: a case report. [PDF]

Front Psychiatry
Wang Q, Ji Z, Wang Y, Qi Z.
europepmc   +1 more source

Recognition of unnatural base pairs by a eukaryotic DNA polymerase enables universal sequencing of an expanded genetic alphabet. [PDF]

Nucleic Acids Res
Luo H, Du Y, Sun L, Ye F, Ma J, Wang X, Wang Y, Chen T.   +7 more
europepmc   +1 more source

Machine Learning-Enhanced Structure-Based Gaussian Expansion for Efficient Wavepacket Calculations. [PDF]

J Phys Chem Lett
Koshiba T, Kanno M, Misaizu F, Kono H.
europepmc   +1 more source

Effects of High-Flow-Velocity Stress on Energy Metabolism and Transcription Level of <i>Triplophysa orientalis</i>. [PDF]

Biology (Basel)
Gao X, Wan H, Jiang Y, Qiu L, Jiang Z, Meng S, Song C.   +6 more
europepmc   +1 more source