Results 101 to 110 of about 6,131,287 (277)
On a Logistic Approximation to the Normal and Other Cumulative Distribution Functions
This paper proposes an approach that maintains the simplicity of various approximations as well as having a closed- form algebraic inverse yet easily generalizable to the approximation of other cumulative distribution functions.
Roberto N. Padua +2 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Reliability Assessment for Small-Sample Accelerated Life Tests with Normal Distribution
A significant challenge in the accelerated life test (ALT) is the reliance on large sample sizes and multiple stress levels, which results in high costs and long test durations.
Jianchao Guo, Huimin Fu
doaj +1 more source
Evaluating the Normal Distribution [PDF]
This article provides a little table-free C function that evaluates the normal distribution with absolute error less than 8 x 10 ^-16 . A small extension provides relative error near the limit available in double precision: 14 to 16 digits, the limits ...
George Marsaglia
core +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Analysis and assessment of the validity dough "theory of functions of the complex variable"
In article the analysis of quality of the "Theory of Functions of a Complex Variable" test is carried out. The dough validity in normal way to distribution, according to the contents, on the distinguishing ability is estimated.
Lidiya A. Muratova
doaj
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

