Results 41 to 50 of about 159,573 (229)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Normal forms of Hopf Singularities: Focus Values Along with some Applications in Physics
پژوهشهای ریاضی, 2018 This paper aims to introduce the original ideas of normal form theory and bifurcation analysis and control of small amplitude limit cycles in a non-technical terms so that it would be comprehensible to wide ranges of Persian speaking engineers and ...
Majid Gazor, Nasrin Sadri
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Slow invariant manifold of heartbeat model [PDF]
, 2014 A new approach called Flow Curvature Method has been recently developed in a book entitled Differential Geometry Applied to Dynamical Systems. It consists in considering the trajectory curve, integral of any n-dimensional dynamical system as a curve in ...
Ginoux, Jean-Marc, Rossetto, Bruno
core
Initial Conditions for Models of Dynamical Systems
, 1994 The long-time behaviour of many dynamical systems may be effectively predicted by a low-dimensional model that describes the evolution of a reduced set of variables.
A.J. Roberts +33 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Semiotics of Global Warming: Combating Semiotic Corrruption [PDF]
, 2007 The central focus of this paper is the disjunction between the findings of climate science in revealing the threat of global warming and the failure to act appropriately to these warnings. The development of climate science can be illuminated through the
Gare, Arran
core
Nonlinear resonances of water waves
, 2009 In the last fifteen years, a great progress has been made in the understanding of the nonlinear resonance dynamics of water waves. Notions of scale- and angle-resonances have been introduced, new type of energy cascade due to nonlinear resonances in the ...
Kartashova, Elena
core +6 more sources