Results 41 to 50 of about 84,144,549 (259)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The normal and the scanning normal form of nonlinear dynamical systems

Mathematical and Computer Modelling, 1990
In this paper a new analytical technique for constructing a normalizing change of variables is presented. The Generalized Normal Form Method allows one to widen substantially the class of dynamic systems suitable for normalization and to include new kinds of dynamic systems in the method scheme which have never been considered previously. The procedure
openaire   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Quantum theory of reactive scattering in phase space [PDF]

, 2010
We review recent results on quantum reactive scattering from a phase space perspective. The approach uses classical and quantum versions of normal form theory and the perspective of dynamical systems theory.
Brandas, E, Wiggins, S.,, Stephen Wiggins, Waalkens, Holger, Waalkens, H., Roman Schubert, Goussev, Arseni, Schubert, Roman, Wiggins, S., Waalkens, H.,, Holger Waalkens, Wiggins, Stephen, Goussev, A., Nicolaides, CA, Schubert, R., Goussev, A.,, Arseni Goussev, Schubert, R.,   +17 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Normal form maps for grazing bifurcations in n-dimensional piecewise-smooth dynamical systems [PDF]

Physica D: Nonlinear Phenomena, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Di Bernardo, M, Budd, C, Champneys, AR
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A generalized frequency detuning method for multidegree-of-freedom oscillators with nonlinear stiffness [PDF]

, 2013
In this paper, we derive a frequency detuning method for multi-degree-of-freedom oscillators with nonlinear stiffness. This approach includes a matrix of detuning parameters, which are used to model the amplitude dependent variation in resonant ...
Neild, S.A, Neild, Simon A, Wagg, D.J, Wagg, David J   +3 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source