Results 51 to 60 of about 12,042 (291)

Deep Learning for Bifurcation Detection: Extending Early Warning Signals to Dynamical Systems with Coloured Noise

Mathematics
Deep learning models have demonstrated remarkable success in recognising tipping points and providing early warning signals. However, there has been limited exploration of their application to dynamical systems governed by coloured noise, which ...
Yazdan Babazadeh Maghsoodlo, Daniel Dylewsky, Madhur Anand, Chris T. Bauch   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The normal and the scanning normal form of nonlinear dynamical systems

Mathematical and Computer Modelling, 1990
In this paper a new analytical technique for constructing a normalizing change of variables is presented. The Generalized Normal Form Method allows one to widen substantially the class of dynamic systems suitable for normalization and to include new kinds of dynamic systems in the method scheme which have never been considered previously. The procedure
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Global Hopf bifurcation in the ZIP regulatory system [PDF]

, 2015
Regulation of zinc uptake in roots of Arabidopsis thaliana has recently been modeled by a system of ordinary differential equations based on the uptake of zinc, expression of a transporter protein and the interaction between an activator and inhibitor ...
Ptashnyk, Mariya, Ptashnyk, Mariya; id_orcid, Claus, Juliane, Chavarría-Krauser, Andrés, Bohmann, Ansgar   +4 more
core   +1 more source

Normal form maps for grazing bifurcations in n-dimensional piecewise-smooth dynamical systems [PDF]

Physica D: Nonlinear Phenomena, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Di Bernardo, M, Budd, C, Champneys, AR
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Quantum theory of reactive scattering in phase space

, 2010
We review recent results on quantum reactive scattering from a phase space perspective. The approach uses classical and quantum versions of normal form theory and the perspective of dynamical systems theory.
Brandas, E, Wiggins, S.,, Stephen Wiggins, Waalkens, Holger, Waalkens, H., Roman Schubert, Goussev, Arseni, Schubert, Roman, Wiggins, S., Waalkens, H.,, Holger Waalkens, Wiggins, Stephen, Goussev, A., Nicolaides, CA, Schubert, R., Goussev, A.,, Arseni Goussev, Schubert, R.,   +17 more
core   +1 more source