Results 121 to 130 of about 4,084,972 (304)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Analysis of Risk Factors for Normal Glucose Tolerance-Hyperinsulinemia [PDF]

, 2018
The aim of this paper is to study the prevalence of individuals with normal glucose tolerance-hyperinsulinemia in Nanshan of Shenzhen, determine the cut point values of normal glucose tolerance-hyperinsulinemia, and investigate the risk factors for it ...
Li, MD, Lian, Nie, MD, Lei, Ye, MD, Xiaoman, Yu, MD, Ming, Ai, MD, Wei, Zhong, MD, Zhibiao, Chi, MD, Lianxiang   +6 more
core  

Left ventricular deformation and fibrosis in obese subjects with normal and impaired glucose tolerance.

, 2015
Abbreviations: cIB, calibrated integrated backscatter, SRa, late diastolic strain rate, SRe, early diastolic strain rate, SRs, systolic strain rateLeft ventricular deformation and fibrosis in obese subjects with normal and impaired glucose tolerance.
Pik-to Cheung (817104), Yiu-fai Cheung (292747), Lijian Xie (817102), Elim Man (817103)   +3 more
core   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

The correlation between insulin sensitivity and circulating zonulin in participants with normal glucose tolerance (NGT, n = 82) and with glucose intolerance (GI, n = 41).

, 2013
The correlation between insulin sensitivity and circulating zonulin in participants with normal glucose tolerance (NGT, n = 82) and with glucose intolerance (GI, n = 41).
Wifredo Ricart (161462), Mònica Sabater (5652220), Francisco Ortega (188515), José María Moreno-Navarrete (322512), José Manuel Fernández-Real (5652223)   +4 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Evaluation of glucose tolerance by OGTT.

, 2013
Oral glucose tolerance test was performed in each group (n = 6) of mice after 6 weeks of aerobic exercise. Values are means ± SEM. NC = normal chow control; HC = HFD control; HE = HFD exercise.
Yanmei Niu (104136), Wenyan Niu (104150), Xiaolei Liu (104141), Li Fu (85791), Hairui Yuan (104130), Fengying Yang (104146)   +5 more
core   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Association between single-nucleotide polymorphism in the islet amyloid polypeptide gene and beta-cell dysfunction in type 2 diabetes mellitus

Al-Azhar Assiut Medical Journal
Background and aim The rising worldwide incidence of type 2 diabetes mellitus (T2DM) highlights the importance of elucidating its genetic determinants, with particular focus on islet amyloid polypeptide (IAPP) and its impact on β-cell dysfunction.
Mohamed H.M. Hasan, Mohamed S.A. Rahman Allam, Sara A. Mohamed, Ahmed A.E. Elhagary   +3 more
doaj   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source