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Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming

Advanced Science, EarlyView.
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva, Virginia Marcia Concato‐Lopes, Fatima Bedier, Lauren Newman, Diana Kitka, Jamelle Brown, Blandine Victor, Minhyung Kim, Tatyana Vagner, Catherine Grasso, Dmitriy Sheyn, Sungyong You, Michael R. Freeman, Fayyaz S. Sutterwala, Helen S. Goodridge, Caroline Jefferies, Paola de Candia, Jlenia Guarnerio, Dolores Di Vizio   +18 more
wiley   +1 more source

CORRIGENDUM FOR "Increased Rates of Meal Absorption Do Not Explain Elevated 1-Hour Glucose in Subjects With Normal Glucose Tolerance". [PDF]

J Endocr Soc, 2019
europepmc   +1 more source

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Diabetic Nephropathy and Proliferative Retinopathy With Normal Glucose Tolerance

Diabetes Care, 1985
A 61-yr-old man presented with the nephrotic syndrome and normal oral glucose tolerance. Renal biopsy showed the nodular (Kimmelstiel-Wilson) and diffuse glomerulosclerosis lesions characteristic of diabetes. Direct ophthalmoscopy and fluorescein angiography demonstrated a picture of advanced proliferative diabetic retinopathy.
J Y, Chan, E, Cole, A K, Hanna
exaly   +3 more sources

Elevated One-Hour Post-Load Plasma Glucose Levels Identifies Subjects With Normal Glucose Tolerance but Early Carotid Atherosclerosis

Atherosclerosis, 2009
To examine whether individuals with normal glucose tolerance (NGT), whose 1-h post-load plasma glucose is >or=155 mg/dl, or with impaired glucose tolerance (IGT) have an increased carotid intima-media thickness (IMT), as compared with NGT individuals ...
Francesco Andreozzi, Giorgio Sesti, Franco Arturi   +2 more
exaly   +2 more sources

The normal glucose-tolerance pattern

Oral Surgery, Oral Medicine, Oral Pathology, 1960
Abstract 1. 1. On the basis of the over-all glucose-tolerance pattern, 100 routine dental patients appear normal if judged by the standards for glucose established by Mosenthal and Barry. 2. 2. From an analysis of the mean two-hour determination of the glucose-tolerance pattern, 100 routine dental patients would be regarded as systemically ...
E, CHERASKIN, L, MANSON-HING
openaire   +2 more sources

Progression of normal glucose tolerance to impaired glucose tolerance or diabetes in the elderly

Diabetes Research and Clinical Practice, 1997
Factors predicting impared glucose tolerance (IGT) and diabetes (DM) were studied in a community-living population aged 70 years or over, with initial normal glucose tolerance (NGT). The baseline examinations from 1991 to 1992 included an oral glucose tolerance test (OGTT), physical examinations and questionnaires.
L, Hiltunen, S L, Kivelä, E, Läärä, S, Keinänen-Kiukaanniemi   +3 more
openaire   +2 more sources

GLUCOSE AND CORTISONE-GLUCOSE TOLERANCE IN NORMAL AND "PREDIABETIC" HUMANS

Annals of Internal Medicine, 1961
Excerpt Detection of the potential diabetic is a principal objective of clinicians and many investigators.
T H, LAMBERT, R B, JOHNSON, G R, PAUL
openaire   +2 more sources

Glucose Turnover in Hyperthyroid Patients with Normal Glucose Tolerance*

The Journal of Clinical Endocrinology & Metabolism, 1989
To determine the diabetogenic effect(s) of thyroid hormones, we simultaneously measured glucose turnover in six hyperthyroid patients and six normal subjects. All had normal fasting blood glucose concentration and oral glucose tolerance test values. We determined hepatic total glucose output (HTGO) and total glucose phosphorylation with [2-3H]glucose ...
S G, Karlander, A, Khan, A, Wajngot, O, Torring, M, Vranic, S, Efendić   +5 more
openaire   +2 more sources

Prevalence of Retinopathy in People With Diabetes, Impaired Glucose Tolerance, and Normal Glucose Tolerance

Diabetes Care, 1998
OBJECTIVE Recently, an international expert committee published new revised criteria for diagnosing diabetes. According to the new criteria, the 2-h glucose level for diabetes in the oral glucose tolerance test (OGTT) is the same as in the previous World Health Organization criteria, but the cut point for the ...
U, Rajala, M, Laakso, Q, Qiao, S, Keinänen-Kiukaanniemi   +3 more
openaire   +2 more sources