Results 61 to 70 of about 1,017,506 (258)
An Affordable Insole-Sensor-Based Trans-Femoral Prosthesis for Normal Gait
This paper proposes a novel and an affordable lower limb prosthesis to enable normal gait kinematics for trans-femoral amputees. The paper details the design of a passive prosthesis with magneto-rheological (MR) damping system and electronic control.
Srinivas Pandit +5 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Spectral decompositions and nonnormality of boundary integral operators in acoustic scattering - extended version [PDF]
Understanding the spectral properties of boundary integral operators in acoustic scattering has important practical implications, such as for the analysis of the stability of boundary element discretisations or the convergence of iterative solvers as the
Betcke, T, Phillips, J, Spence, EA
core
The stresses in a closed lipid membrane described by the Helfrich hamiltonian, quadratic in the extrinsic curvature, are identified using Noether's theorem.
Boal D +20 more
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A unified model of time perception accounts for duration-based and beat-based timing mechanisms
Accurate timing is an integral aspect of sensory and motor processes such as the perception of speech and music and the execution of skilled movement. Neuropsychological studies of time perception in patient groups and functional neuroimaging studies of ...
Sundeep eTeki +3 more
doaj +1 more source
Multicriterion Synthesis of Intelligent Control Systems of Generating Unit of Nuclear Power Station [PDF]
The paper is devoted to solution of some problems in nuclear power station generating unit intellectual control systems using genetic algorithms on the basis of control system model development, optimizations methods of their direct quality indices and ...
Jafari Henjani, Seyed Mojtaba +1 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Collaborative Role of Counselors in Inclusive Schools
Strengthening Inclusive Education requires the role of various parties in educational institutions including guidance and counseling. Guidance and counseling services at the Inclusive Schools currently oriented towards developmental guidance and ...
Redita Yuliawanti
doaj +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

