Results 121 to 130 of about 15,343,912 (311)

Violation of LGtI inequalities in the light of NO $$\nu $$ ν A and T2K anomaly

European Physical Journal C: Particles and Fields
The recent anomaly observed in NO $$\nu $$ ν A and T2K experiments in standard three-flavor neutrino oscillation could potentially signal physics extending beyond the standard model (SM).
Lekhashri Konwar, Juhi Vardani, Bhavna Yadav   +2 more
doaj   +1 more source

A novel approach to quantifying the sensitivity of current and future cosmological datasets to the neutrino mass ordering through Bayesian hierarchical modeling

Physics Letters B, 2017
We present a novel approach to derive constraints on neutrino masses, as well as on other cosmological parameters, from cosmological data, while taking into account our ignorance of the neutrino mass ordering.
Martina Gerbino, Massimiliano Lattanzi, Olga Mena, Katherine Freese   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Still another approach to the braid ordering

, 2005
We develop a new approach to the linear ordering of the braid group $B\_n$, based on investigating its restriction to the set $\Div(\Delta\_n^d)$ of all divisors of $\Delta\_n^d$ in the monoid $B\_\infty^+$, i.e., to positive $n$-braids whose normal form
Dehornoy, Patrick
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

More models for lepton mixing with four constraints

Journal of High Energy Physics, 2019
We propose new lepton-mixing textures that may be enforced through well-defined symmetries in renormalizable models. Each of our textures has four sum rules for the neutrino mass observables.
Darius Jurčiukonis, Luís Lavoura
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Predictive Pati-Salam theory of fermion masses and mixing

Journal of High Energy Physics, 2017
We propose a Pati-Salam extension of the standard model incorporating a flavor symmetry based on the Δ (27) group. The theory realizes a realistic Froggatt-Nielsen picture of quark mixing and a predictive pattern of neutrino oscillations.
A. E. Cárcamo Hernández, Sergey Kovalenko, José W. F. Valle, C. A. Vaquera-Araujo   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source