Results 31 to 40 of about 29,952 (214)

Establishment and molecular profiling of a PDX model of a metachronous brain tumor in a patient with constitutional mismatch repair deficiency with biallelic MSH6 variant

Animal Models and Experimental Medicine, EarlyView.
A 6½‐year‐old girl was diagnosed with a medulloblastoma, SHH activated, subtype 3 and TP53 mutant (somatic). After surgery and chemotherapy, she was monitored with quarterly magnetic resonance imaging (MRI) scans and remained free of disease for almost 4 years.
Daniel Antunes Moreno, Bruna Minniti Mançano, Mirella Baroni, Eric Allison Philot, Felipe Antonio de Oliveira Garcia, Murilo Bonatelli, Flávia Escremim de Paula, Iara Viana Vidigal Santana, Gustavo Ramos Teixeira, Mauricio Yamanari, Luciane Sussuchi da Silva, André Escremim de Paula, Augusto Perazzolo Antoniazzi, Adrian Willig, Xiaobin Xing, Zhenyu Xu, Lucas Lourenço, Carlos Almeida Junior, Silvia Aparecida Teixeira, Rui Manuel Reis   +19 more
wiley   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Tasha K. Phillips, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +16 more
wiley   +1 more source

Blake's pouch cyst-like imaging abnormalities in idiopathic normal pressure hydrocephalus

Brain Disorders
Objective: Blake's pouch cyst is a cause of congenital non-communicating hydrocephalus. Recent study revealed that adult onset communicating normal pressure hydrocephalus sometimes accompanied by Blake's pouch cyst-like imaging abnormalities.
Yumiko Saito, Toru Baba, Wataru Narita, Shigenori Kanno, Shunji Mugikura, Yasuko Tatewaki, Yoshiyuki Nishio, Osamu Iizuka, Yasuyuki Taki, Teiji Tominaga, Etsuro Mori, Kyoko Suzuki   +11 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Neuroimaging in normal pressure hydrocephalus

Dementia & Neuropsychologia
Normal pressure hydrocephalus (NPH) is a syndrome characterized by the triad of gait disturbance, mental deterioration and urinary incontinence, associated with ventriculomegaly and normal cerebrospinal fluid (CSF) pressure.
Benito Pereira Damasceno
doaj   +1 more source

Hakim-Adams syndrome: An unusual cause of reversible postoperative coma.

Frontiers in Medicine, 2016
We report the case of a 72 years old patient presenting in our ICU with persistent postoperative coma in a context of recent unexplored neurological dysfunction. Detailed medical history taking from the patient’s family revealed he recently suffered from
Mohamed SALEH, Marine Bouex
doaj   +1 more source

Relationships Between Lateral Ventricle Size, Cerebrospinal Fluid Dynamics, and Aqueductal Resistance in Young Healthy Adults

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Ventricular enlargement and abnormal cerebrospinal fluid (CSF) circulation are closely associated in communicating hydrocephalus (NPH), yet their causal relationship remains unclear. Studying healthy populations may help clarify these mechanisms.
Pan Liu, Jiachen Xie, Kimi Owashi, Yann Attekeble, Jean‐Marc Constans, Cyrille Capel, Olivier Balédent   +6 more
wiley   +1 more source

Imaging Markers for Normal Pressure Hydrocephalus: An Overview

Biomedicines, 2023
Idiopathic bormal pressure hydrocephalus (iNPH) is a neurological syndrome that clinically presents with Hakim’s triad, namely cognitive impairment, gait disturbances, and urinary incontinence.
Efstratios-Stylianos Pyrgelis, Georgios Velonakis, Sokratis G. Papageorgiou, Leonidas Stefanis, Elisabeth Kapaki, Vasilios C. Constantinides   +5 more
doaj   +1 more source

5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus [PDF]

, 2021
Antti Junkkari, Harri Sintonen, Nils Danner, H. K. Jyrkkänen, Tuomas Rauramaa, Antti Luikku, Anne M. Koivisto, RP Roine, Heimo Viinamäki, Hilkka Soininen, Juha E. Jääskeläinen, Ville Leinonen   +11 more
openalex   +1 more source

Pulsatile Tinnitus as the Primary Symptom in IIH: A Distinct Clinical Entity

The Laryngoscope, EarlyView.
ABSTRACT Objective To compare patients with idiopathic intracranial hypertension (IIH) who present with pulsatile tinnitus (PT) to the Otolaryngology service with those with IIH who present with more classical symptoms to non‐otolaryngologists. Methods Chart query confirmed all patients diagnosed with PT and IIH (by modified Friedman criteria).
Daniel H. Coelho, Warren Felton, Scott Haines, Nauman F. Manzoor, Aristides Sismanis   +4 more
wiley   +1 more source