Results 51 to 60 of about 30,703 (243)

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Blake's pouch cyst-like imaging abnormalities in idiopathic normal pressure hydrocephalus

Brain Disorders
Objective: Blake's pouch cyst is a cause of congenital non-communicating hydrocephalus. Recent study revealed that adult onset communicating normal pressure hydrocephalus sometimes accompanied by Blake's pouch cyst-like imaging abnormalities.
Yumiko Saito, Toru Baba, Wataru Narita, Shigenori Kanno, Shunji Mugikura, Yasuko Tatewaki, Yoshiyuki Nishio, Osamu Iizuka, Yasuyuki Taki, Teiji Tominaga, Etsuro Mori, Kyoko Suzuki   +11 more
doaj   +1 more source

Can Shunt Response in Patients with Idiopathic Normal Pressure Hydrocephalus Be Predicted from Preoperative Brain Imaging? A Retrospective Study of the Diagnostic Use of the Normal Pressure Hydrocephalus Radscale in 119 Patients

, 2022
BACKGROUND AND PURPOSE: The Normal Pressure Hydrocephalus Radscale is a combined scoring of 7 different structural imaging markers on preoperative brain CT or MR imaging in patients with idiopathic normal pressure hydrocephalus: callosal angle, Evans ...
Hansen, A. E., Munch, T.N., Backlund, A.D.L., Holst, A.V., Holst, A. V., Hasselbalch, S. G., Backlund, A. D.L., Mardal, C.A., Carlsen, J.F., Carlsen, J. F., Munch, T. N., Hasselbalch, S.G., Hansen, A.E., Mardal, C. A., Taudorf, S.   +14 more
core   +1 more source

Gait Analysis in Idiopathic Normal Pressure Hydrocephalus: A Single Centre Experience [PDF]

, 2023
Introduction:Gait impairment is the earliest symptom of idiopathic normal pressure hydrocephalus (iNPH). This study objectively investigates gait changes using Ambulatory Parkinson’s Disease Monitoring inertial sensors after cerebrospinal fluid ...
Atay Vural, Atilla Deniz Kahraman, Hussein Youssef, Kardelen Akar, Esra Özkan, Mustafa Yavuz Samancı, Özgür Öztop-Çakmak   +6 more
core   +1 more source

Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam, Niroshan Jeyakumar, Gobishan Jeyakumar, Florence Chang, Duncan Wilson, Paloma Becker, Hugo Morales‐Briceno, Neil Mahant, Victor S.C. Fung   +8 more
wiley   +1 more source

Normal Pressure Hydrocephalus

Disease-a-Month, 2010
Normal pressure hydrocephalus (NPH) is increasingly recognized as a treatable cause of gait disturbance, cognitive decline, and urinary incontinence in the aging population. The impact of treatment on both improved quality of life and decreased need for institutional care is potentially very great, and will only increase as the population ages.
openaire   +3 more sources

Normal-pressure hydrocephalus: A critical review

Dementia & Neuropsychologia, 2019
. Normal-pressure hydrocephalus (NPH) is a potentially reversible syndrome characterized by enlarged cerebral ventricles (ventriculomegaly), cognitive impairment, gait apraxia and urinary incontinence.
Louise Makarem Oliveira, Ricardo Nitrini, Gustavo C. Román   +2 more
doaj   +1 more source

Differential Progression of Neuroinflammation in Patients with Isolated Rapid‐Eye‐Movement Sleep Behavior Disorder

Movement Disorders, EarlyView.
Abstract Background Neuroinflammation, measured using [11C](R)‐PK11195 positron emission tomography (PET), has been reported in isolated rapid‐eye‐movement sleep behavior disorder (iRBD), but its temporal progression is unknown. Objective The aim was to assess longitudinal progression of neuroinflammation in iRBD patients and its relationship with ...
Andreas Myhre Baun, Alex Iranzo, Miriam Højholt Terkelsen, Rainer Hinz, Morten Gersel Stokholm, Kristian Stær, Mónica Serradel, Marit Otto, Kristina Bacher Svendsen, Alicia Garrido, Dolores Vilas, Arne Møller, Carles Gaig, Eduardo Tolosa, David J. Brooks, Per Borghammer, Simon Fristed Eskildsen, Nicola Pavese   +17 more
wiley   +1 more source

Doxapram Exposure Was Not Associated With Adverse Neurodevelopmental Outcomes in Very Low Birth Weight Infants: A Monocentric Retrospective Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Doxapram is used as an additional therapy for apnea of prematurity when standard treatments such as caffeine or continuous positive airway pressure are insufficient, but its impact on long‐term neurodevelopment remains uncertain. This study evaluated the association between Doxapram exposure and neurodevelopmental outcomes in very low ...
Thomas Müller, Alexandros Rahn, Sabine Pirr, Corinna Peter, Carolin Böhne, Bettina Bohnhorst   +5 more
wiley   +1 more source

Hakim-Adams syndrome: An unusual cause of reversible postoperative coma.

Frontiers in Medicine, 2016
We report the case of a 72 years old patient presenting in our ICU with persistent postoperative coma in a context of recent unexplored neurological dysfunction. Detailed medical history taking from the patient’s family revealed he recently suffered from
Mohamed SALEH, Marine Bouex
doaj   +1 more source