Results 41 to 50 of about 46,311 (239)

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Normal Pressure Hydrocephalus: New Concepts [PDF]

open access: yesDüşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2008
Normal pressure hydrocephalus is a treatable syndrome seen in elderly patients who show the classical triad of gait disorder, dementia and urinary incontinence. It may be due to idipathic or secondary causes and is a progressive psychomotor disorder.
Mehmet Murat Taşkın
doaj  

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Gait and frontal lobe function become associated in patients with idiopathic normal pressure hydrocephalus after shunt surgery

open access: yesFrontiers in Neurology
ObjectiveThe association between gait and cognition in older adults is well-established. This study investigated the association between gait and cognition, especially in the frontal lobe, in patients with idiopathic normal pressure hydrocephalus (iNPH).
Masatsune Ishikawa   +3 more
doaj   +1 more source

Clinical Features of Pediatric Idiopathic Intracranial Hypertension and Applicability of New ICHD-3 Criteria [PDF]

open access: yes, 2018
Idiopathic intracranial hypertension (IIH) is characterized by intracranial pressure >28 cmH2O in the absence of identifiable causes. Aim of this paper is to describe the clinical phenotype of pediatric IIH and to analyze the applicability of ICHD-3 ...
Barbara Battan   +8 more
core   +2 more sources

Chiari I Malformation: Review and Update of Current Treatment Options

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo   +11 more
wiley   +1 more source

NORMAL PRESSURE HYDROCEPHALUS FOLLOWING MYODIL MYELOGRAPHY

open access: yesInternational Journal of Integrated Health Sciences, 2015
Objective: Fat-saturated contrast agent-enhanced myelography was used for the purpose of diagnosing most spinal lesions from the beginning of the 19th century until the end of the 20th century.
Ezgi Akar, Mehmet Ufuk Akmil
doaj   +1 more source

Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease [PDF]

open access: yes, 1995
Neurological examination of a lethargic, ataxic 12-week-old dobermann revealed decreased conscious proprioception in all its limbs. Haematological examination revealed a low platelet count.
Dunn, J.K.   +3 more
core   +2 more sources

Clinical use and radiological yield of magnetic resonance fingerprinting in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Magnetic resonance fingerprinting (MRF) is a novel paradigm for magnetic resonance imaging (MRI) that efficiently generates multiparametric quantitative tissue property maps with a single acquisition. Its quantitative nature offers many advantages over conventional MRI.
Maksim Parfyonov   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy