Results 61 to 70 of about 29,037 (213)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Normal pressure hydrocephalus presenting as delusional disorder

Industrial Psychiatry Journal, 2015
Normal pressure hydrocephalus (NPH) is caused by aqueductal stenosis resulting in syndrome of gait disturbance, cognitive impairment, and urinary incontinence. Late onset psychosis should be evaluated thoroughly to rule out any organic cause.
Shruti Srivastava, Manjeet Singh Bhatia, Priyanka Gautam   +2 more
doaj   +1 more source

Human cerebral arterial morphogenesis explored by 3D microscopic imaging of cleared embryos: Bridging the gap between embryonic and adult anatomy

Journal of Anatomy, EarlyView.
We provide a description of human embryonic cerebral arterial development based on whole‐mount immunostaining, tissue clearing, three‐dimensional (3D) light‐sheet microscopy imaging, and anatomically informed virtual segmentation of human embryos. Findings are compared with adult radiological anatomy. We provide a detailed account of the development of
Eimad Shotar, Raphaël Blain, Aymeric Nadjem, Nermine Saidi, Megumi Inoue, Daniel Smith‐Paredes, Miccaella Vergara, Armelle Lesaunier, Quentin Rappeneau, Joséphine Blevinal, Gérard Couly, Julien Burel, Julien Allard, Kevin Premat, Stéphanie Lenck, Pierre‐Marie Chiaroni, Erwah Kalsoum, Maryne Toupin, Séverine Mazaud‐Guittot, Diane Rebourcet, Paolo Giacobini, Olivier Naggara, Hugo Gortais, Grégoire Boulouis, Alexis Guédon, Philippe Gailloud, Frédéric Glicenstein, Anaïs Favre, Frédéric Clarençon, Yorick Gitton, Alain Chédotal   +30 more
wiley   +1 more source

Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén, Anna Lindam, Dan Farahmand, Anne‐Marie Landtblom, Katarina Laurell   +4 more
wiley   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Psychotic behavior in normal pressure hydrocephalus

Indian Journal of Psychiatry
Normal pressure hydrocephalus (NPH) usually presents with progressive gait impairment, urinary incontinence, and cognitive deficits. Many studies have shown that NPH can mimic other disorders like Parkinson disease with tremors and rigidity.
Janani Shankar, Ramnarayan Ramachandran
doaj   +1 more source

Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 4, December 2026.
We report a case of neurosyphilis characterized by early‐onset dementia, limbic encephalitis, and normal pressure hydrocephalus. Psychiatrists should be aware of the possibility of neurosyphilis in such cases. ABSTRACT Background Neurosyphilis may present with a variety of clinical symptoms and neuroimaging findings and is thus likely to be overlooked.
Naoki Obata, Kenshi Terajima, Gen Miura, Yuta Muratake, Shun Irie, Yuichiro Watanabe   +5 more
wiley   +1 more source

Levels of selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in patients with hydrocephalus

Folia Neuropathologica, 2017
Cytokines are widely known mediators of inflammation accompanying many neurodegenerative disorders including normal pressure hydrocephalus (NPH). NPH is caused by impaired cerebrospinal fluid (CSF) absorption and treated by surgical shunt insertion.
Kinga Czubowicz, Mariusz Głowacki, Ewa Fersten, Ewa Kozłowska, Robert P. Strosznajder, Zbigniew Czernicki   +5 more
doaj   +1 more source

High‐Resolution IVIM MRI Characterizes Diffusion–Perfusion Properties of the Parasagittal Dura

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
Parasagittal dura demonstrates intermediate diffusion and elevated perfusion‐related IVIM metrics compared with brain parenchyma, reflecting its unique microfluidic environment at the CSF–dura interface. IVIM imaging of the parasagittal dura provides a rapid, noncontrast MRI approach to assess dural fluid transport and may offer a potential imaging ...
Yi‐Jui Liu, Chun‐Han Liao, Shin‐Lei Peng, Shao‐Chieh Lin, Chao‐Chun Lin, Chia‐Wei Lin, Chia‐Hong Hsieh, Chun‐Wen Chen, Hing‐Chiu Chang   +8 more
wiley   +1 more source

Pericerebral spaces as diagnostic signposts in fetal central nervous system pathologies

Ultrasound in Obstetrics &Gynecology, EarlyView.
L. Guibaud, S. Cabet
wiley   +1 more source