Results 81 to 90 of about 29,952 (214)

Effects of Non‐Aspirin Nonsteroidal Anti‐Inflammatory Drugs on Acute Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, Volume 12, Issue 11, Page 2328-2334, November 2025.
ABSTRACT Objective Despite celecoxib, a cyclooxygenase‐2 inhibitor, promoting functional recovery from intracerebral hemorrhage (ICH) by reducing inflammation‐mediated perihematomal edema in rat models, the evidence of its effects on patient outcomes remains limited.
Shin‐Joe Yeh, Sung‐Chun Tang, Li‐Kai Tsai, Jiann‐Shing Jeng   +3 more
wiley   +1 more source

Application of LRG mechanism in normal pressure hydrocephalus

Heliyon
Normal pressure hydrocephalus (NPH) is a prevalent type of hydrocephalus, including secondary normal pressure hydrocephalus (SNPH) and idiopathic normal pressure hydrocephalus (INPH).
Luyao Ma, Wencai Wang, Yongqiang Zhao, Menghao Liu, Wei Ye, Xianfeng Li   +5 more
doaj   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

Advanced Science, Volume 12, Issue 42, November 13, 2025.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang, Wenye Wang, Yidong Peng, Weiji Weng, Hanyu Wei, Qiyuan Feng, Antian Wang, Minjie Hu, Zhuoran Li, Shenyu Sun, Zhenghui He, Daiwen Zhang, Wenlan Qi, Yuhan Han, Zixuan Ma, Jiyuan Hui, Ru Gong, Yingwei Gao, Yong Lin, Jiyao Jiang, Xiaoling Gao, Junfeng Feng   +21 more
wiley   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear, Paul Kalitsis, Melissa Glass, Bertrand Isidor, Catherine Vincent‐Delorme, Florence Petit, Judith M. A. Verhagen, Alexander Jorge, Ana Cristina Victorino Krepischi, Ikeoluwa Osei‐Owusu, Eva Martinez, Anne O'Donnell‐Luria, Nicole de Leeuw, Sarah Ruggiero, Ingo Helbig, Francis David I, Natasha J. Brown   +16 more
wiley   +1 more source

Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract A neuropathology examination after death remains the gold standard for differentiating between Alzheimer disease (AD) and AD and related dementias (ADRD). Increasing interest and familiarity with digital imaging highlights recent shifts to modernize pathology workflows by leveraging technology that automates imaging and analysis.
Aaron M. Rosado, Juan C. Vizcarra, Shivam R. Rai Sharma, Cristopher Dirk Keene, Charles L. White III, Ain Kim, Shelley L. Forrest, Gabor G. Kovacs, Chen‐Nee Chuah, Margaret E. Flanagan, Thomas M. Pearce, Brittany N. Dugger, David A. Gutman   +12 more
wiley   +1 more source

17 years of experience with shunt systems in normal pressure hydrocephalus - From differential pressure to gravitational valves

World Neurosurgery: X
Objective: Complication rate of shunting for normal pressure hydrocephalus (NPH) has significantly improved over the last decades. Especially the use of overdrainage protection has reduced the incidence of subdural hematoma and collections.
Julian Zipfel, Cristina Kohlmann-Dell’Acqua, Susan Noell, Leonidas Trakolis   +3 more
doaj   +1 more source

Blood‐based Alzheimer's disease biomarkers in a behavioral neurology clinic: Real‐world implementation, clinical utility, and diagnostic performance

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Blood‐based biomarkers (BBMs) for Alzheimer's disease (AD), including plasma phosphorylated tau (p‐tau), are increasingly used in clinical practice, but “real‐world” implementation patterns, context‐of‐use (COU), clinical utility, and diagnostic performance are incompletely understood. METHODS A retrospective analysis of the first
Igor Prufer Q C Araujo, Tara Ellingson, Nicholas U. Schwartz, Connor D. Dietz, Gautam Tammewar, Kaancan Deniz, Manizhe Eslami‐Amirabadi, Andrew G. Breithaupt, Marci Rosenberg, Nhat Minh Bui, Yasmeen Gonzalez, Renaud La Joie, Peter A. Ljubenkov, Katherine L. Possin, Julio C. Rojas, David N. Soleimani‐Meigooni, Yingbing Wang, Adam M. Staffaroni, Melanie L. Stephens, Elena Tsoy, Charles C. Windon, Adam L. Boxer, Gil D. Rabinovici, Bruce L. Miller, Lawren VandeVrede   +24 more
wiley   +1 more source

Impact of Subjective Evaluations in Predicting Response to Ventriculoperitoneal Shunt for Idiopathic Normal Pressure Hydrocephalus

, 2022
Mahmoud Messerer, Marius Blanchard, Kyriakos Papadimitriou, Alberto Vandenbulcke, Dionys Rutz, Valérie Beaud, Ehab Shiban, Julien F. Bally, Gilles Allali, Roy Thomas Daniel, Giulia Cossu   +10 more
openalex   +1 more source

Watching the eye with Mars in sight

Experimental Physiology, EarlyView.
Peter zu Eulenburg, Lonnie Petersen, Damian M. Bailey   +2 more
wiley   +1 more source