Results 21 to 30 of about 787,863 (229)

Virtually free finite-normal-subgroup-free groups are strongly verbally closed

open access: yes, 2018
Any virtually free group $H$ containing no non-trivial finite normal subgroup (e.g., the infinite dihedral group) is a retract of any finitely generated group containing $H$ as a verbally closed subgroup.Comment: 6 pages. V2: minor corrections.
Klyachko, Anton A.   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Pseudocomplementation in (Normal) Subgroup Lattices [PDF]

open access: yesCommunications in Algebra, 2010
The goal of this article is to study finite groups admitting a pseudocomplemented subgroup lattice (PK-groups) or a pseudocomplemented normal subgroup lattice (PKN-groups). In particular, we obtain a complete classification of finite PK-groups and of finite nilpotent PKN-groups. We also study groups with a Stone normal subgroup lattice, and we classify
De Medts, Tom, Tărnăuceanu, Marius
openaire   +2 more sources

Some Characterizations of a Normal Subgroup of a Group [PDF]

open access: yes, 2012
Let G be a group and H be a subgroup of G which is either finite or of finite index in G. In this note, we give some characterizations for normality of H in G.
Kakkar, Vipul, Shukla, R. P.
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Normal subgroups contained in the Frattini subgroup. II [PDF]

open access: yesProceedings of the American Mathematical Society, 1975
If p p is an odd prime and H H is a p p -group with a characteristic subgroup K K such that | K | > | K ∩ Z ( H ) | = p
openaire   +2 more sources

Normal Subsystems of Fusion Systems

open access: yes, 2010
In this article we prove that for any saturated fusion system, that the (unique) smallest weakly normal subsystem of it on a given strongly closed subgroup is actually normal.
~Craven, David A.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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