Results 81 to 90 of about 5,621,576 (372)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Products of Normal Supersolvable Subgroups [PDF]
Proceedings of the American Mathematical Society, 1971 It is shown in this paper that if G is a finite group which is the product of two normal supersolvable subgroups of relatively prime index, then G is supersolvable.
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Algebraic Characteristics of Anti-Intuitionistic Fuzzy Subgroups Over a Certain Averaging Operator
IEEE Access, 2020 In this paper, we propose the concept of ρ anti-intuitionistic fuzzy sets, ρ anti - intuitionistic fuzzy subgroups and prove some of their algebraic properties.
Dilshad Alghazzawi +4 more
doaj +1 more source
Gaussian Measure of Normal Subgroups
The Annals of Probability, 1983 Let $(\mu_t)_{t>0}$ be a Gaussian semigroup on a metric, separable, complete group $G$. If $H$ is a Borel measurable normal subgroup of $G$ such that $\mu_t(H) > 0$ for all $t$, then $\mu_t(H) = 1$ for every $t$. If, in addition, $\mu_t$ are symmetric, then $\mu_t(H) > 0$ for a single $t$ implies $\mu_t(H) = 1$ for all $t$.
Byczkowski, T., Hulanicki, A.
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
PERFECTLY STABLE AND NORMAL SUBGROUPS
Proceedings of the YSU A: Physical and Mathematical Sciences, 2022 The equivalence between the concepts of normal and perfectly stable subgroups is shown. The proof of the main theorem is based on a novel concept of hypergroups over a group.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source