Results 101 to 110 of about 526,031 (267)
‘Successful Ageing’ in Practice: Reflections on Health, Activity and Normality in Old Age in Sweden
Culture Unbound: Journal of Current Cultural Research, 2012 This article aims to contribute to the critical examination of the notions of health and activity, and to discuss how these cultural and social constructs have impact on elderly people’s lives. An ethnographic perspective gives fruitful inputs to explore
Åsa Alftberg, Susanne Lundin
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Determination of reliability, validity and norm of California critical thinking skills test, form B
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2003 Background and Objective: The purpose of this research was to investigate the reliability, validity and norm of CCTST F.S. The California critical thinking skills test (CCTST) contains 34 multi-choice questions with a correct answer in the five critical ...
A Davoodi, P Naghsh Poor
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
When normality collapses from one moment to the next. A sociological theory of singular crisis
Frontiers in SociologySince the emergence of sociology, it has been part of the discipline’s self-image to diagnose crises in modern societies. Sociology, however, has no theory that differentiates between normal and extranormal or singular crises. In this article, we want to
Klaus Kraemer, Joris Steg
doaj +1 more source
Evaluation of Four Tests When Normality and Homogeneity of Variance Assumptions are Violated [PDF]
, 2003 Mehmet Mendeş, Akin Pala .
openalex +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Rank Correlation and Tests of Significance Involving No Assumption of Normality [PDF]
, 1936 Harold Hotelling +1 more
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On the singularities and on the projective normality of some Enriques–Fano threefolds
, 2023 Vincenzo Martello
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source