Results 71 to 80 of about 526,031 (267)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Statistical Assumptions of Substantive Analyses across the General Linear Model: A Mini-Review
Frontiers in Psychology, 2012 The validity of inferences drawn from statistical test results depends on how well data meet associated assumptions. Yet, research (e.g., Hoekstra, Kiers, & Johnson, 2012) indicates that such assumptions are rarely reported in literature and that ...
Kim F Nimon
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Normal Jonsson theories and their Kaiser classes
Қарағанды университетінің хабаршысы. Математика сериясыWe present results concerning new notion connected with the study of Jonsson theories. The new notion is a Kaiser class of models for arbitrary Jonsson theories.
A.R. Yeshkeyev +2 more
doaj +1 more source
Sensors, 2019 Oscillometric blood pressure (BP) monitors currently estimate a single point but do not identify variations in response to physiological characteristics.
Soojeong Lee +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Shapiro–Wilk Test with Known Mean
Revstat Statistical Journal, 2016 An adaptation of the Shapiro–Wilk W test to the case of normality with a known mean is considered. The table of critical values for different sample sizes and several significance levels is given.
Zofia Hanusz +2 more
doaj +1 more source
General M-estimates for contaminated p th-order autoregressive processes: Consistency and asymptotic normality [PDF]
, 1982 Oscar H. Bustos
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source