Results 101 to 110 of about 1,041,285 (289)

Solutions with prescribed mass for the Sobolev critical Schrödinger–Poisson system with p-Laplacian

Bulletin of Mathematical Sciences
In this paper, we are concerned with the existence and properties of ground states for the quasilinear Schrödinger–Poisson system with combined critical nonlinearities −Δpu+γϕ|u|p−2u=λ|u|p−2u+μ|u|q−2u+|u|p∗−2uin ℝ3,−Δϕ=|u|pin ℝ3, having prescribed mass ...
Kai Liu, Xiaoming He
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Normalized solutions of NLS equations with mixed nonlocal nonlinearities

Advances in Nonlinear Analysis
We study the existence and nonexistence of normalized solutions for the nonlinear Schrödinger equation with mixed nonlocal nonlinearities: −Δu=λu+μ(Iα∗∣u∣p)∣u∣p−2u+(Iα∗∣u∣q)∣u∣q−2uinRN,∫RN∣u∣2dx=c,\left\{\begin{array}{ll}-\Delta u=\lambda u+\mu \left({I ...
Zhang Zhenyu, Sun Juntao
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Normalized solutions to a class of (2, q)-Laplacian equations

Advanced Nonlinear Studies
This paper is concerned with the existence of normalized solutions to a class of (2, q)-Laplacian equations in all the possible cases with respect to the mass critical exponents 2(1 + 2/N), q(1 + 2/N).
Baldelli Laura, Yang Tao
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Blow-up solutions to the Hartree-Fock type Schrödinger equation with the critical rotational speed

Advances in Nonlinear Analysis
In this article, we are concerned with the existence, non-existence, and blow-up behavior of normalized ground state solutions for the mass critical Hartree-Fock type Schrödinger equation with rotation i∂tu=−Δu+2V(x)u+2ΩLzu−λu−bu∫RN∣u(y)∣2∣x−y∣2dy,(t,x ...
Tu Yuanyuan, Wang Jun
doaj   +1 more source

Solution of rank deficient normals

, 1981
Technical note written as input to the early studies of the ESA space astrometry project Hipparcos.
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Normalized solutions for Sobolev critical Schrodinger-Bopp-Podolsky systems

Electronic Journal of Differential Equations, 2023
Yuxin Li, Xiaojun Chang, Zhaosheng Feng
doaj