Results 41 to 50 of about 1,041,285 (289)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Multiple normalized solutions to the nonlinear Schrödinger–Poisson system with the $L^2$-subcritical growth

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, we study the existence of multiple normalized solutions to the following Schrödinger–Poisson system with general nonlinearities: \begin{equation*} \begin{cases} -\varepsilon^2\Delta u+V(x)u+\phi u=f(u)+\lambda u & \hbox{in $\mathbb{R}
Siwei Wei, Kaimin Teng
doaj   +1 more source

Exact Solutions of the Schr\"odinger Equation via Laplace Transform Approach: Pseudoharmonic potential and Mie-type potentials

, 2011
Exact bound state solutions and corresponding normalized eigenfunctions of the radial Schr\"odinger equation are studied for the pseudoharmonic and Mie-type potentials by using the Laplace transform approach.
Arda, Altug, Sever, Ramazan
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Existence and non-degeneracy of the normalized spike solutions to the fractional Schrödinger equations

Advances in Nonlinear Analysis
The present study investigates the existence and non-degeneracy of normalized solutions for the following fractional Schrödinger equation: (−Δ)su+V(x)u=aup+μu,x∈RN,u∈Hs(RN){\left(-\Delta )}^{s}u+V\left(x)u=a{u}^{p}+\mu u,\hspace{1.0em}x\in {{\mathbb{R}}}^
Guo Qing, Zhang Yuhang
doaj   +1 more source

Non-Markovian quantum trajectories, instruments and time-continuous measurements

, 2011
The linear and the nonlinear non-Markovian quantum state diffusion equation (NMQSD) are well known tools for the description of certain non-Markovian open quantum systems. In this work, we systematically investigate whether the normalized linear NMQSD or
Krönke, Sven, Strunz, Walter T.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Infinitely many free or prescribed mass solutions for fractional Hartree equations and Pohozaev identities

Advanced Nonlinear Studies
In this paper we study the following nonlinear fractional Hartree (or Choquard-Pekar) equation (−Δ)su+μu=(Iα*F(u))F′(u) inRN, ${\left(-{\Delta}\right)}^{s}u+\mu u=\left({I}_{\alpha }{\ast}F\left(u\right)\right){F}^{\prime }\left(u\right)\quad \text{in} {\
Cingolani Silvia, Gallo Marco, Tanaka Kazunaga   +2 more
doaj   +1 more source

Solvable few-body quantum problems

, 2014
This work is devoted to the study of some exactly solvable quantum problems of four, five and six bodies moving on the line. We solve completely the corresponding stationary Schr\"odinger equation for these systems confined in an harmonic trap, and ...
Bachkhaznadji, A., Lassaut, M.
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source