Results 31 to 40 of about 500,395 (357)
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
, 2018 Constructivist approaches in epistemology and ethics offer a promising account of normativity. But constructivism faces a powerful Schmagency Objection, raised by David Enoch.
Flowerree, A. K.
core
Resisting Reductive Realism [PDF]
, 2020 Ethicists struggle to take reductive views seriously. They also have trouble conceiving of some supervenience failures.
Laskowski, N. G.
core +1 more source
International Theory, 2019 Normativity matters in international politics, but IR scholarship will benefit from de-reifying ‘norms’ as units into a relational, configurational alternative.
S. Pratt
semanticscholar +1 more source
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Folk teleology drives persistence judgments [PDF]
, 2020 Two separate research programs have revealed two different factors that feature in our judgments of whether some entity persists. One program—inspired by Knobe—has found that normative considerations affect persistence judgments. For instance, people are
Rose, David +2 more
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Technology, Normativity, and the Future: the Aristotelian Turn [PDF]
, 1997 In our postmodern era all certainties seem to have gone. Neither the idea of progress nor standard ethical theories have apparently retained enough power to guide humanity. As a result, technologists find themselves in a paradoxical situation. While they
Procee, Henk
core +2 more sources
Managing ethical uncertainty: implicit normativity and the sociology of ethics
Sociology of Health and Illness, 2019 This article illustrates and discusses the idea of ‘implicit normativity’, and specifically its relevance to the management of ethical uncertainty. In particular I consider (i) the role implicit normativity plays in masking and containing potential ...
A. Cribb
semanticscholar +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Two Epistemological Arguments against Two Semantic Dispositionalisms [PDF]
, 2020 Even though he is not very explicit about it, in “Wittgenstein on Rules and Private Language” Kripke discusses two different, albeit related, skeptical theses ‒ the first one in the philosophy of mind, the second one in the metaphysics of language ...
Guardo, Andrea
core +1 more source