Results 61 to 70 of about 41,211 (264)
Background To reduce the coronavirus disease burden in England, along with many other countries, the government implemented a package of non-pharmaceutical interventions (NPIs) that have also impacted other transmissible infectious diseases such as ...
K. O’Reilly+13 more
semanticscholar +1 more source
Actualités sur les norovirus [PDF]
Noroviruses belong to the Caliciviridae family. They are a major cause of sporadic cases and outbreaks of gastroenteritis in all age groups, and are responsible for a considerable disease burden in industrialized countries. Noroviruses are single-stranded RNA viruses, and show great genetic diversity making their detection difficult. Noroviruses can be
de Rougemont, Alexis+3 more
openaire +4 more sources
Genetic Analysis of Human Norovirus Strains in Japan in 2016–2017
In the 2016/2017 winter season in Japan, HuNoV GII.P16-GII.2 strains (2016 strains) emerged and caused large outbreaks of acute gastroenteritis. To better understand the outbreaks, we examined the molecular evolution of the VP1 gene and RdRp region in ...
Koo Nagasawa+20 more
semanticscholar +1 more source
Understanding the relationship between norovirus diversity and immunity
Human noroviruses are the most common viral cause of acute gastroenteritis worldwide. Currently, there are no approved vaccines or specific therapeutics to treat the disease.
Lauren A Ford-Siltz+2 more
semanticscholar +1 more source
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David+8 more
core +1 more source
Forecasting Based on Surveillance Data [PDF]
Forecasting the future course of epidemics has always been one of the main goals of epidemic modelling. This chapter reviews statistical methods to quantify the accuracy of epidemic forecasts. We distinguish point and probabilistic forecasts and describe different methods to evaluate and compare the predictive performance across models.
arxiv +1 more source
Interferon-lambda: A potent regulator of intestinal viral infections [PDF]
Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core +3 more sources
Norovirus assembly and stability
Noroviruses are rapidly evolving RNA viruses and are generally known as the main cause of viral gastroenteritis worldwide. Particle stability is of special interest as transmission occurs via the faecal-oral route and virions are able to persist in the environment.
Ronja Pogan+3 more
openaire +4 more sources
The State of Norovirus Vaccines [PDF]
Noroviruses represent the most important cause of acute gastroenteritis worldwide; however, currently no licensed vaccine exists. Widespread vaccination that minimizes overall norovirus disease burden would benefit the entire population, but targeted vaccination of specific populations such as healthcare workers may further mitigate the risk of severe ...
Kari Debbink+2 more
openaire +3 more sources
Objectives: Norovirus is associated with one-fifth of all gastroenteritis cases, but basic epidemiological data is lacking, especially in developing countries.
Ran-Ran Cao+11 more
doaj