Results 81 to 90 of about 5,888 (174)

CVID Enteropathy Associated With Chronic Norovirus Infection: Background, Clinical Features, and Therapeutic Aspects

open access: yesReviews in Medical Virology, Volume 35, Issue 6, November 2025.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency, characterised by impaired antibody production, immune dysregulation, and a broad spectrum of clinical manifestations. Gastrointestinal involvement is frequent, affecting up to 20% of patients and significantly contributing to morbidity and ...
Györgyi Műzes, Ferenc Sipos
wiley   +1 more source

Tulane virus protease as a structural surrogate for inhibitor screening of human norovirus proteases

open access: yesJournal of Virology
Human norovirus (HuNoV) is a significant cause of gastroenteritis worldwide, affecting people of all age groups. There are currently no vaccines or drugs available, leaving susceptible populations vulnerable to severe or protracted illness.
Son Pham   +6 more
doaj   +1 more source

Laboratory efforts to cultivate noroviruses

open access: yesJournal of General Virology, 2004
Noroviruses (NoVs) are a leading cause of gastroenteritis worldwide and are recognized as the foremost cause of foodborne illness. Despite numerous efforts, routine cell cultures have failed to yield replicating NoV. This paper describes methods used to try to grow NoV in vitro in two laboratories.
Duizer, E   +5 more
openaire   +3 more sources

Natural Norovirus Infections in Rhesus Macaques

open access: yesEmerging Infectious Diseases, 2016
Using a recently developed real-time reverse transcription PCR, I retested 500 fecal samples from rhesus macaques collected in 2008. Previous conventional reverse transcription PCR testing identified 1 isolate of GII norovirus; retesting found GI, GII ...
Tibor Farkas
doaj   +1 more source

Caliciviridae Other Than Noroviruses [PDF]

open access: yesViruses, 2019
Besides noroviruses, the Caliciviridae family comprises four other accepted genera: Sapovirus, Lagovirus, Vesivirus, and Nebovirus. There are six new genera proposed: Recovirus, Valovirus, Bavovirus, Nacovirus, Minovirus, and Salovirus. All Caliciviridae have closely related genome structures, but are genetically and antigenically highly diverse and ...
openaire   +4 more sources

Hospitalization due to norovirus and genotypes of rotavirus in pediatric patients, state of Espírito Santo

open access: yesMemorias do Instituto Oswaldo Cruz, 2008
Viruses are the leading cause for hospitalization due to gastroenteritis worldwide. Group A rotaviruses (RV) are the most prevalent and are assorted in glycoproteins (G) and protease sensitive (P) dual genotypes based on polymorphic genes that encode the
Leandro Rua Ribeiro   +6 more
doaj   +1 more source

Phylogenetic Analyses Suggest that Factors Other Than the Capsid Protein Play a Role in the Epidemic Potential of GII.2 Norovirus

open access: yesmSphere, 2017
Norovirus is the leading cause of acute gastroenteritis worldwide. For over two decades, a single genotype (GII.4) has been responsible for most norovirus-associated cases. However, during the winter of 2014 to 2015, the GII.4 strains were displaced by a
Kentaro Tohma   +3 more
doaj   +1 more source

VIRAL ETIOLOGY ACUTE INTESTINAL INFECTIONS MOLECULAR MONITORING IN CHILDREN’S HOSPITAL

open access: yesИнфекция и иммунитет, 2015
On the territory of the Russian Federation in the overall structure of acute intestinal infections the proportion of viral diarrhea among children varies from 24 to 78% of cases depending on the season.
A. V. Sergeeva   +7 more
doaj   +1 more source

The problem of norovirus infection in animals (literature review)

open access: yesВетеринария сегодня
Livestock industry efficiency strongly depends on the livability of young animals, mainly during the early postnatal period. Infectious gastroenteritis of newborns manifested as diarrhea occupies the leading place among the diseases of young animals and ...
V. А. Mischenko   +5 more
doaj   +1 more source

Noroviruses: Recent Updates

open access: yesPediatric Gastroenterology, Hepatology & Nutrition, 2012
Noroviruses (NoVs) are one major etiologic agent in acute gastroenteritis (AGE) in all ages and are the primary cause of food-borne gastroenteritis worldwide. GII-4 NoVs has predominated since 1990s, and novel recombinant strains have been reported worldwide.
openaire   +1 more source

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