Results 81 to 90 of about 8,806 (201)
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede +14 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Map of the relative frequencies of rotaviruses and noroviruses detected in each region of this study.
Lauren A. Rackoff (394170) +3 more
core +1 more source
Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah +14 more
wiley +1 more source
Pathogenesis of Noroviruses, Emerging RNA Viruses
Human noroviruses in the family Caliciviridae are a major cause of epidemic gastroenteritis. They are responsible for at least 95% of viral outbreaks and over 50% of all outbreaks worldwide.
Karst, Stephanie M. Karst
core +1 more source
Zusammenfassung Hintergrund und Zielsetzung Das bullöse Pemphigoid (BP) ist die häufigste blasenbildende Autoimmunerkrankung in der westlichen Welt. Während die Mehrheit der Patienten mit BP durch die langfristige Anwendung von Kortikosteroiden mit oder ohne Immunmodulatoren/Immunsuppressiva Remissionen erreicht, empfehlen nationale und internationale ...
Maike M. Holtsche +7 more
wiley +1 more source
Final Consumer Options to Control and Prevent Foodborne Norovirus Infections
Norovirus (NoV) causes about one-fifth of all cases of foodborne diseases and is a foremost cause of domestically acquired foodborne acute gastroenteritis and outbreaks.
Susana Guix +2 more
doaj +1 more source
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva +8 more
wiley +1 more source

