Results 71 to 80 of about 15,637 (259)

Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

mBio, 2020
Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic
Kei Haga, Khalil Ettayebi, Victoria R. Tenge, Umesh C. Karandikar, Miranda A. Lewis, Shih-Ching Lin, Frederick H. Neill, B. Vijayalakshmi Ayyar, Xi-Lei Zeng, Göran Larson, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes   +12 more
doaj   +1 more source

Benchmarking State-of-the-Art Approaches for Norovirus Genome Assembly in Metagenome Sample

Biology, 2023
A recently published article in BMCGenomics by Fuentes-Trillo et al. contains a comparison of assembly approaches of several noroviral samples via different tools and preprocessing strategies.
Dmitry Meleshko, Anton Korobeynikov
doaj   +1 more source

Noroviruses in oysters

, 2021
SE; PDF; Efsa.focalpoint@slv ...
Ottoson, Jakob, Toljander, Jonas
openaire   +1 more source

Diagnostic Accuracy of Immunochromatographic Tests for the Detection of Norovirus in Stool Specimens: a Systematic Review and Meta-Analysis

Microbiology Spectrum, 2021
Noroviruses are the leading cause of acute gastroenteritis in all age groups and constitute a major health and economic burden worldwide. This systematic review and meta-analysis aimed to determine the diagnostic accuracy of immunochromatographic tests ...
Seo Hee Yoon, Hye Rim Kim, Jong Gyun Ahn
doaj   +1 more source

Emergence of a novel GII.17 norovirus – end of the GII.4 era? [PDF]

, 2015
In the winter of 2014/15 a novel GII.P17-GII.17 norovirus strain (GII.17 Kawasaki 2014) emerged, as a major cause of gastroenteritis outbreaks in China and Japan.
Ambert-Balay, K., Beek, J.H.G.M. (Janko) van, Bucardo, F., Chan, M.C., Graaf, M.T. (Marieke) de, Hewitt, J. (Joanne), Iritani, N., Koopmans D.V.M., M.P.G. (Marion), Lynch, M., Mans, J., Nordgren, J., Podkolzin, A.T., Rasmussen, L.D., Reuter, G. (Gabor), Templeton, K.E., Vennema, H. (Harry), Vinjé, J. (Jan), Vito Martella, White, P.A.   +18 more
core   +3 more sources

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

bioRxiv, 2019
Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have combined proteomic analysis of the viral translation and replication complexes with a CRISPR screen,
M. Hosmillo, Jia Lu, Michael R. McAllaster, J. Eaglesham, Xinjie Wang, E. Emmott, P. Domingues, Y. Chaudhry, T. Fitzmaurice, Matthew Tung, M. Panas, G. McInerney, Nicholas Locker, Craig B. Willen, I. Goodfellow   +14 more
semanticscholar   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

The Role of the Gut Microbiome in Resisting Norovirus Infection as Revealed by a Human Challenge Study

mBio, 2020
Norovirus infections take a heavy toll on worldwide public health. While progress has been made toward understanding host responses to infection, the role of the gut microbiome in determining infection outcome is unknown.
N. V. Patin, A. Peña-Gonzalez, J. K. Hatt, C. Moe, A. Kirby, K. T. Konstantinidis   +5 more
doaj   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah, Denver P. Linklater, Vassil Tzanov, Chaitali Dekiwadia, Sergey Rubanov, Phuc H. Le, Laleh Tafakori, Ranya Simons, Graeme Moad, Soichiro Saita, Takashi Yanagishita, Hideki Masuda, Vladimir Baulin, Natalie A. Borg, Elena P. Ivanova   +14 more
wiley   +1 more source