Results 71 to 80 of about 8,806 (201)
VIEW, Volume 7, Issue 5, October 2026.Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source
Inhibition of noroviruses by piperazine derivatives [PDF]
Bioorganic & Medicinal Chemistry Letters, 2012 There is currently an unmet need for the development of small-molecule therapeutics for norovirus infection. The piperazine scaffold, a privileged structure embodied in many pharmacological agents, was used to synthesize an array of structurally-diverse derivatives which were screened for anti-norovius activity in a cell-based replicon system.
Dou, Dengfeng +6 more
openaire +3 more sources
Immobilization of murine noroviruses in a cultivated phaeozem soil and its reversibility
, 2017 Immobilization of murine noroviruses in a cultivated phaeozem soil and its reversibility.
Tesson, Vincent +3 more
core +2 more sources
Features of the clinical course and approaches to the therapy of norovirus infection in children
Лечащий Врач, 2021 The frequency, nature and duration of extra-intestinal manifestations depending on the therapy in children with norovirus infection were studied. It was found that in norovirus infection in children, in addition to gastrointestinal symptoms, there are ...
R. V. Popova, T. A. Ruzhentsova
doaj
Analysis of amino acid variation in the P2 domain of the GII-4 norovirus VP1 protein reveals putative variant-specific epitopes. [PDF]
PLoS ONE, 2008 BACKGROUND: Human noroviruses are a highly diverse group of viruses classified into three of the five currently recognised Norovirus genogroups, and contain numerous genotypes or genetic clusters.
David J Allen +4 more
doaj +1 more source
Experimental Physiology, Volume 111, Issue 10, Page 4507-4524, 1 October 2026.Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto +3 more
wiley +1 more source
Surface Composition and Temperature Interact to Shape Viral Survival and Growth
Environmental Microbiology, Volume 28, Issue 9, September 2026.Environmental surface type and temperature interact synergistically to shape viral survival and reproduction. Using bacteriophages T4 and φX174 on copper, steel and plastic at different temperatures, we demonstrate that survival and reproductive capacity are partially decoupled traits, with copper at 37°C causing rapid viral inactivation while their ...
Ketty Kabengele +3 more
wiley +1 more source
Genetic and evolutionary perspectives on genogroup III, genotype 2 bovine noroviruses
, 2013 peer reviewedBovine noroviruses are enteric pathogens that are detected in stool samples from cattle. Five genogroups are currently described in the genus Norovirus (family Caliciviridae), and within the genogroups, sequences are further divided into ...
Mauroy, Axel +5 more
core +1 more source
THE ETIOLOGIC SPECTRUM OF PATHOGENS OF VIRAL GASTROENTERITIS IN CHILDREN FROM BAKU
Детские инфекции (Москва), 2016 The article presents the results of research on the study of etiology, the logical structure of viral diarrhea in Baku (Azerbaijan) in 2015. It was found that more than half (62.6%), gastroenteritis in children of viral etiology, of which the leading ...
N. N. Aliev +4 more
doaj +1 more source
Microbiology Spectrum, 2023 Monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA on inanimate surfaces plays a crucial role in environmental surveillance, enabling the indirect detection of infected individuals and facilitating rapid infection control ...
Kouichi Kitamura +2 more
doaj +1 more source