Results 51 to 60 of about 8,445 (167)
Prevalence of acute intestinal infections and their role in human pathology (review)
Acute intestinal infections (AII) are one of the most common infectious diseases, the eighth most important cause of annual mortality among all age groups, and the fifth most common cause of death among children under 5 years of age worldwide. From 3 to
E. V. Kozishkurt
doaj +3 more sources
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Features of the clinical course and approaches to the therapy of norovirus infection in children
The frequency, nature and duration of extra-intestinal manifestations depending on the therapy in children with norovirus infection were studied. It was found that in norovirus infection in children, in addition to gastrointestinal symptoms, there are ...
R. V. Popova, T. A. Ruzhentsova
doaj
Analysis of amino acid variation in the P2 domain of the GII-4 norovirus VP1 protein reveals putative variant-specific epitopes. [PDF]
BACKGROUND: Human noroviruses are a highly diverse group of viruses classified into three of the five currently recognised Norovirus genogroups, and contain numerous genotypes or genetic clusters.
David J Allen +4 more
doaj +1 more source
Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede +14 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Noroviruses in healthcare settings: a challenging problem
Current knowledge about noroviruses in relation to healthcare-associated infections (HCAIs) merely scratches the surface. Most data come from outbreak-based studies, which represent only a small piece of the puzzle.
Koopmans, M.
core +1 more source
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Pathogenesis of Noroviruses, Emerging RNA Viruses
Human noroviruses in the family Caliciviridae are a major cause of epidemic gastroenteritis. They are responsible for at least 95% of viral outbreaks and over 50% of all outbreaks worldwide.
Karst
core +1 more source
THE ETIOLOGIC SPECTRUM OF PATHOGENS OF VIRAL GASTROENTERITIS IN CHILDREN FROM BAKU
The article presents the results of research on the study of etiology, the logical structure of viral diarrhea in Baku (Azerbaijan) in 2015. It was found that more than half (62.6%), gastroenteritis in children of viral etiology, of which the leading ...
N. N. Aliev +4 more
doaj +1 more source

