Results 41 to 50 of about 8,445 (167)
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source
Norovirus infections take a heavy toll on worldwide public health. While progress has been made toward understanding host responses to infection, the role of the gut microbiome in determining infection outcome is unknown.
N. V. Patin +5 more
doaj +1 more source
Benchmarking State-of-the-Art Approaches for Norovirus Genome Assembly in Metagenome Sample
A recently published article in BMCGenomics by Fuentes-Trillo et al. contains a comparison of assembly approaches of several noroviral samples via different tools and preprocessing strategies.
Dmitry Meleshko, Anton Korobeynikov
doaj +1 more source
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto +3 more
wiley +1 more source
Structural Evolution of the Emerging 2014-2015 GII.17 Noroviruses
Recent reports suggest that human genogroup II genotype 17 (GII.17) noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains.
Koromyslova, A +4 more
core +1 more source
Molecular Characterization of Noroviruses Detected in Diarrheic Stools of Michigan and Wisconsin Dairy Calves: Circulation of Two Distinct Subgroups [PDF]
Noroviruses have emerged as the leading worldwide cause of acute non-bacterial gastroenteritis in humans. The presence of noroviruses in diarrheic stool samples from calves on Michigan and Wisconsin dairy farms was investigated by RT-PCR.
Lora E Hanson +11 more
core +1 more source
Noroviruses are the leading cause of acute gastroenteritis in all age groups and constitute a major health and economic burden worldwide. This systematic review and meta-analysis aimed to determine the diagnostic accuracy of immunochromatographic tests ...
Seo Hee Yoon, Hye Rim Kim, Jong Gyun Ahn
doaj +1 more source
Surface Composition and Temperature Interact to Shape Viral Survival and Growth
Environmental surface type and temperature interact synergistically to shape viral survival and reproduction. Using bacteriophages T4 and φX174 on copper, steel and plastic at different temperatures, we demonstrate that survival and reproductive capacity are partially decoupled traits, with copper at 37°C causing rapid viral inactivation while their ...
Ketty Kabengele +3 more
wiley +1 more source
Review of Animal Noroviruses [PDF]
Among enteric caliciviruses, noroviruses belong to the genus Norovirus, one of the four accepted genera in the family Caliciviridae. These single-stranded, positive-sense RNA viruses are highly variable both genetically and antigenically.
Mauroy, A. +3 more
core
Norovirus Escape from Broadly Neutralizing Antibodies Is Limited to Allostery-Like Mechanisms
Ideal antiviral vaccines elicit antibodies (Abs) with broad strain recognition that bind to regions that are difficult to mutate for escape. Using 10 murine norovirus (MNV) strains and 5 human norovirus (HuNoV) virus-like particles (VLPs), we identified ...
Abimbola O. Kolawole +8 more
doaj +1 more source

