Results 31 to 40 of about 8,806 (201)
Epidemiology and evolution of rotaviruses and noroviruses from an archival WHO Global Study in Children (1976-79) with implications for vaccine design. [PDF]
PLoS ONE, 2013 Prompted by the discovery of new gastrointestinal viruses, the NIH, NIAID and WHO investigated the etiology of acute diarrhea that occurred from 1976-1979 in a global cohort of infants and young children.
Lauren A Rackoff +3 more
doaj +1 more source
Seroprevalence of Noroviruses in Swine [PDF]
Journal of Clinical Microbiology, 2005 ABSTRACT Noroviruses (NVs) are important human pathogens that cause acute gastroenteritis. Genetically related animal enteric NVs have also been described, but there is no evidence of interspecies transmission of NVs. In this study we characterized antibody prevalence among domestic pigs by using recombinant capsid antigens of two human NVs ...
Tibor, Farkas +5 more
openaire +2 more sources
Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors
Viruses, 2019 Proteases are a major enzyme group playing important roles in a wide variety of biological processes in life forms ranging from viruses to mammalians. The aberrant activity of proteases can lead to various diseases; consequently, host proteases have been
Kyeong-Ok Chang +4 more
doaj +1 more source
Glycolysis Is an Intrinsic Factor for Optimal Replication of a Norovirus
mBio, 2019 The metabolic pathways of central carbon metabolism, glycolysis and oxidative phosphorylation (OXPHOS), are important host factors that determine the outcome of viral infections and can be manipulated by some viruses to favor infection.
Karla D. Passalacqua +8 more
doaj +1 more source
Molecular Characterization of Noroviruses Detected in Diarrheic Stools of Michigan and Wisconsin Dairy Calves: Circulation of Two Distinct Subgroups [PDF]
, 2004 Noroviruses have emerged as the leading worldwide cause of acute non-bacterial gastroenteritis in humans. The presence of noroviruses in diarrheic stool samples from calves on Michigan and Wisconsin dairy farms was investigated by RT-PCR.
Lora E Hanson +11 more
core +1 more source
mSphere, 2016 Although two in vitro cultivation methods have been reported, discrimination of infectious human norovirus particles for study of viral inactivation is still a challenge, as both rely on reverse transcriptase quantitative PCR.
Matthew D. Moore +3 more
doaj +1 more source
mBio, 2020 Human noroviruses (HuNoV) are a leading cause of viral gastroenteritis worldwide and a significant cause of morbidity and mortality in all age groups.
Myra Hosmillo +9 more
doaj +1 more source
Noroviruses in food chain production [PDF]
, 2016 Viruses, predominantly noroviruses, are progressively identified as the leading cause of foodborne diseases worldwide. In the Europe Union they have been determined as a main cause of foodborne outbreaks in 2014, while in the United States viruses are ...
Radin, Dragoslava
core +1 more source
In Vitro Cell Culture Infectivity Assay for Human Noroviruses [PDF]
, 2007 Human noroviruses cause severe, self-limiting gastroenteritis that typically lasts 24–48 hours. Because of the lack of suitable tissue culture or animal models, the true nature of norovirus pathogenesis remains unknown.
Abbaszadegan, Morteza A. +21 more
core +1 more source
Norovirus Polymerase Fidelity Contributes to Viral Transmission
mSphere, 2016 Intrahost genetic diversity and replication error rates are intricately linked to RNA virus pathogenesis, with alterations in viral polymerase fidelity typically leading to attenuation during infections in vivo.
Armando Arias +4 more
doaj +1 more source