Results 21 to 30 of about 5,888 (174)
Epidemiology and evolution of rotaviruses and noroviruses from an archival WHO Global Study in Children (1976-79) with implications for vaccine design. [PDF]
PLoS ONE, 2013 Prompted by the discovery of new gastrointestinal viruses, the NIH, NIAID and WHO investigated the etiology of acute diarrhea that occurred from 1976-1979 in a global cohort of infants and young children.
Lauren A Rackoff +3 more
doaj +1 more source
Seroprevalence of Noroviruses in Swine [PDF]
Journal of Clinical Microbiology, 2005 ABSTRACT Noroviruses (NVs) are important human pathogens that cause acute gastroenteritis. Genetically related animal enteric NVs have also been described, but there is no evidence of interspecies transmission of NVs. In this study we characterized antibody prevalence among domestic pigs by using recombinant capsid antigens of two human NVs ...
Tibor, Farkas +5 more
openaire +2 more sources
Veterinary Clinics of North America: Small Animal Practice, 2011 Noroviruses are recognized as emerging enteric pathogens of humans and have been identified in recent years in a number of mammalian species. The role of noroviruses as pathogens in immune-competent animals and under natural conditions remains uncertain, although both homologous and heterologous animal models are now available to investigate the ...
MARTELLA, Vito +2 more
openaire +3 more sources
Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors
Viruses, 2019 Proteases are a major enzyme group playing important roles in a wide variety of biological processes in life forms ranging from viruses to mammalians. The aberrant activity of proteases can lead to various diseases; consequently, host proteases have been
Kyeong-Ok Chang +4 more
doaj +1 more source
Glycolysis Is an Intrinsic Factor for Optimal Replication of a Norovirus
mBio, 2019 The metabolic pathways of central carbon metabolism, glycolysis and oxidative phosphorylation (OXPHOS), are important host factors that determine the outcome of viral infections and can be manipulated by some viruses to favor infection.
Karla D. Passalacqua +8 more
doaj +1 more source
mSphere, 2016 Although two in vitro cultivation methods have been reported, discrimination of infectious human norovirus particles for study of viral inactivation is still a challenge, as both rely on reverse transcriptase quantitative PCR.
Matthew D. Moore +3 more
doaj +1 more source
mBio, 2020 Human noroviruses (HuNoV) are a leading cause of viral gastroenteritis worldwide and a significant cause of morbidity and mortality in all age groups.
Myra Hosmillo +9 more
doaj +1 more source
Norovirus Polymerase Fidelity Contributes to Viral Transmission
mSphere, 2016 Intrahost genetic diversity and replication error rates are intricately linked to RNA virus pathogenesis, with alterations in viral polymerase fidelity typically leading to attenuation during infections in vivo.
Armando Arias +4 more
doaj +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Introduction. Human Noroviruses (HuNoV) are highly contagious pathogens responsible of acute human norovirus infection (HuNoVI). GII.4 is the prevailing norovirus genotype in the incidence of gastroenteritis worldwide.
Roman O. Bykov +8 more
doaj +1 more source
Characterization of New Recombinant Noroviruses [PDF]
Journal of Clinical Microbiology, 2005 ABSTRACT Noroviruses are important etiologic agents of acute gastroenteritis and show great genetic diversity. To characterize more fully previously detected strains that could not be assigned unequivocally to one particular genotype based on the RNA polymerase, we have sequenced a region in the capsid gene and, in some cases, in the junction
Ambert Balay, K +4 more
openaire +3 more sources