Results 151 to 160 of about 5,411,218 (297)

Research on Quality Management Information System for Marine Ecological Early Warning Monitoring Throughout the Process

open access: yesHaiyang Kaifa yu guanli
Based on operational requirements for quality management, an information technology platform is designed and developed, which covers the entire business process of marine ecological early warning and monitoring, by applying technologies such as SOA ...
ZHENG Lin   +6 more
doaj  

Dataset of ocean vessel traffic in the North Sea. [PDF]

open access: yesData Brief, 2023
Meyer R   +4 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Confluence : Spring/Summer 2018

open access: yes
Confluence is a newsletter of Oregon Sea Grant.
Oregon State University. Sea Grant College Program
core   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

North Sea Manuscript data

open access: yes
All data associated to published article "Tidal and seasonal influence on cold seep activity and methanotroph efficiency in the North Sea" in Nature Communications Earth ...
de Groot, Tim
core   +1 more source

Confluence : Spring/Summer 2018 - print version

open access: yes
Confluence is a newsletter of Oregon Sea Grant.
Oregon State University. Sea Grant College Program
core   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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