Results 161 to 170 of about 1,748,176 (291)

North Sea oil [PDF]

Nature, 1974
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effects of bound-wave asymmetry on North Sea rogue waves. [PDF]

Sci Rep
Knobler S, Malila MP, Tayfun MA, Liberzon D, Fedele F.   +4 more
europepmc   +1 more source

Screening for Influenza and Morbillivirus in Seals and Porpoises in the Baltic and North Sea. [PDF]

Pathogens, 2023
Stokholm I, Baechlein C, Persson S, Roos A, Galatius A, Kyhn LA, Sveegaard S, Thøstesen CB, Olsen MT, Becher P, Siebert U.   +10 more
europepmc   +1 more source

Inventory of current and future presence of non-wind sea use functions [PDF]

In order to assess the suitability of locations on the Central and Southern North Sea for wind parks present sea use functions should also be taken into account.
Jongbloed, R.H., Leopold, M.F., Quirijns, F.J., Slijkerman, D.M.E., Wal, J.T., van der   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Persistent Infection in Harbor Seals 12-13 Years after Phocine Distemper Virus Epizootics in 1988 and 2002, North Sea. [PDF]

Emerg Infect Dis
van de Bildt MWG, Rijks JM, Jensen TH, Brasseur SMJM, Kik MJL, Osterhaus ADME, Gröne A, Kuiken T, IJzer J.   +8 more
europepmc   +1 more source

Acoustic monitoring reveals spatiotemporal occurrence of Nathusius' pipistrelle at the southern North Sea during autumn migration. [PDF]

Environ Monit Assess, 2023
Lagerveld S, Wilkes T, van Puijenbroek MEB, Noort BCA, Geelhoed SCV.   +4 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

A taxonomically reliable DNA barcode reference library for North Sea macrobenthos. [PDF]

Sci Data
Christodoulou M, Derycke S, Beentjes KK, Hillewaert H, Laakmann S, Lundin K, Kamyab E, Khodami S, Maes S, Reiss H, Uhlir C, Van den Bulcke L, Van der Hoorn B, De Backer A, Arbizu PM.   +14 more
europepmc   +1 more source