Results 211 to 220 of about 54,464 (302)

A novel tRF-Gly is associated with obesity development through post-transcriptional regulation of lipid metabolism. [PDF]

Cell Mol Biol Lett
Lei Y, Gan M, Wang K, Liao T, Yang Y, Zhao X, Zhang X, Chen D, Wang X, Ma J, Niu L, Zhao Y, Chen L, Zhou X, Wang Y, Li M, Zhu L, Shen L.   +17 more
europepmc   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

Outer Membrane Vesicles From <i>Bacteroides fragilis</i> Contain Coding and Non-Coding Small RNA Species That Modulate Inflammatory Signalling in Intestinal Epithelial Cells. [PDF]

J Extracell Biol
Sheikh A, Scano C, Xu J, Ojo T, Conforti JM, Haberman KL, King B, Martinez AS, Pujol M, Watkins J, Lotter J, Lin EL, Zechmann B, Sevcik A, Sayes C, Gallagher ES, Lang SP, Mell J, Ehrlich GD, Taube JH, Greathouse KL.   +20 more
europepmc   +1 more source

Discovery of Viroids and Viroid‐Like RNAs in Plants

Plant Biotechnology Journal, EarlyView.
Zhiyou Xuan, Fei Xing, Xinying Yang, Qingsong Wang, Xiaoru Wang, Song Zhang, Xuedong Liu, Hongbo Jiang, Zongtao Sun, Fang Ren, Shuai Li, Feng Ding, Shifang Li, Changyong Zhou, Zhixiang Zhang, Mengji Cao   +15 more
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

Queuosine is incorporated into precursor tRNA before splicing. [PDF]

Nat Commun
Guo W, Kaczmarczyk I, Kopietz K, Flegler F, Russo S, Cigirgan E, Chramiec-Głąbik A, Koziej Ł, Cirzi C, Peschek J, Reuter K, Helm M, Glatt S, Tuorto F.   +13 more
europepmc   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

RECQ5 mediates pre-rRNA processing in nucleolus. [PDF]

Nucleic Acids Res
Ma Y, Yu X.
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli. [PDF]

Nucleic Acids Res
Lipońska A, Monlezun L, Wilkins I, Ngo S, Oïffer T, Bouchachi C, Hunt JF, Aalberts DP, Boël G.   +8 more
europepmc   +1 more source