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Replication in Human Intestinal Enteroids of Infectious Norovirus from Vomit Samples
Emerging Infectious Diseases, 2021 A typical clinical symptom of human norovirus infection is projectile vomiting. Although norovirus RNA and viral particles have been detected in vomitus, infectivity has not yet been reported.
Marie Hagbom +6 more
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Norwalk Virus Vaccines: Challenges and Progress [PDF]
The Journal of Infectious Diseases, 2000 Human caliciviruses (HuCVs) are the major cause of outbreaks of acute nonbacterial gastroenteritis throughout the world. An increasing recognition of the clinical significance of these viruses as human pathogens causing foodborne and waterborne disease indicates that an effective vaccine would be useful. This article reviews the current challenges that
M K, Estes +6 more
openaire +2 more sources
Viruses, 2019 Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain.
Malak A. Esseili +9 more
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Production of vaccines for treatment of infectious diseases by transgenic plants
Acta Agriculturae Slovenica, 2016 Since the first pathogen antigen was expressed in transgenic plants with the aim of producing edible vaccine in early 1990s, transgenic plants have become a well-established expression system for production of alternative vaccines against various human ...
Kristina LEDL, Zlata LUTHAR
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Chemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA viruses. [PDF]
PLoS ONE, 2014 Most antiviral treatment options target the invading pathogen and unavoidably encounter loss of efficacy as the pathogen mutates to overcome replication restrictions.
Marta J Gonzalez-Hernandez +7 more
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Vomiting as a Symptom and Transmission Risk in Norovirus Illness: Evidence from Human Challenge Studies. [PDF]
PLoS ONE, 2016 In the US, noroviruses are estimated to cause 21 million cases annually with economic losses reaching $2 billion. Outbreak investigations frequently implicate vomiting as a major transmission risk.
Amy E Kirby +2 more
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BMC Microbiology, 2001 Background Norwalk virus causes outbreaks of acute non-bacterial gastroenteritis in humans. The virus capsid is composed of a single 60 kDa protein. In a previous study, the capsid protein of recombinant Norwalk virus genogroup II was expressed in an E ...
Takino Koichi +10 more
doaj +1 more source
Sensitive detection of norovirus using phage nanoparticle reporters in lateral-flow assay. [PDF]
PLoS ONE, 2015 Noroviruses are recognized worldwide as the principal cause of acute, non-bacterial gastroenteritis, resulting in 19-21 million cases of disease every year in the United States. Noroviruses have a very low infectious dose, a short incubation period, high
Anna E V Hagström +9 more
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RASSEGNA DI EPISODI DI GASTROENTERITI ACUTE DA NORWALK LIKE VIRUS
Microbiologia Medica, 2003 -
L.F. Pecone, E. Vecchi, E. Righi
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Viral species richness and composition in young children with loose or watery stool in Ethiopia
BMC Infectious Diseases, 2019 Background Stool consistency is an important diagnostic criterion in both research and clinical medicine and is often used to define diarrheal disease. Methods We examine the pediatric enteric virome across stool consistencies to evaluate differences in ...
Kristen Aiemjoy +10 more
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