Results 41 to 50 of about 27,015 (248)

Investigation of genotype diversity of 7,804 norovirus sequences in humans and animals of China

open access: yesOpen Life Sciences, 2022
Norovirus is a prominent enteric virus responsible for severe acute gastroenteritis disease burden worldwide. In our current study, we analyzed 7,804 norovirus sequences of human and animals in China which were detected from 1980 to 2020 from GenBank ...
Li Manyu   +5 more
doaj   +1 more source

A review of the factors involved in older people's decision making with regard to influenza vaccination: a literature review [PDF]

open access: yes, 2008
Aims and objectives. The aim of this paper was to develop an understanding of the factors involved in older people's decision making with regard to influenza vaccination to inform strategies to improve vaccine uptake and reduce morbidity and mortality.
Andrew MK   +8 more
core   +1 more source

Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response. [PDF]

open access: yesPLoS Pathogens, 2012
Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As obligate intracellular pathogens, viruses have the capacity to manipulate the ubiquitin (Ub) cycle to their advantage by ...
Jeffrey W Perry   +5 more
doaj   +1 more source

Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients. [PDF]

open access: yesPLoS ONE, 2011
Norwalk virus and human papilloma virus, two viruses that infect humans at mucosal surfaces, have been found capable of rapidly penetrating human mucus secretions.
Kaoru Hida   +5 more
doaj   +1 more source

Viral species richness and composition in young children with loose or watery stool in Ethiopia

open access: yesBMC Infectious Diseases, 2019
Background Stool consistency is an important diagnostic criterion in both research and clinical medicine and is often used to define diarrheal disease. Methods We examine the pediatric enteric virome across stool consistencies to evaluate differences in ...
Kristen Aiemjoy   +10 more
doaj   +1 more source

Sensitive detection of norovirus using phage nanoparticle reporters in lateral-flow assay. [PDF]

open access: yesPLoS ONE, 2015
Noroviruses are recognized worldwide as the principal cause of acute, non-bacterial gastroenteritis, resulting in 19-21 million cases of disease every year in the United States. Noroviruses have a very low infectious dose, a short incubation period, high
Anna E V Hagström   +9 more
doaj   +1 more source

Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses [PDF]

open access: yes, 2013
Norovirus (NV) gastroenteritis is a major contributor to global morbidity and mortality, yet little is known about immune mechanisms leading to NV control. Previous studies using the murine norovirus (MNV) model have established a key role for T cells in
Artis, David   +8 more
core   +2 more sources

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

open access: yesPlant Biotechnology Journal, EarlyView.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska   +2 more
wiley   +1 more source

Animal caliciviruses /
Calicivírus animal

open access: yesSemina: Ciências Agrárias, 2008
The caliciviruses were included in Picornaviridae family, and only in 1979 they were classified as Caliciviridae members. There are four genera included in this family: Vesivirus, Lagovirus, Norovirus and Sapovirus.
Amauri Alcindo Alfieri   +2 more
doaj   +1 more source

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