Identification of Gastroenteric Viruses by Electron Microscopy Using Higher Order Spectral Features [PDF]
Background: Many paediatric illnesses are caused by viral agents, for example, acute gastroenteritis. Electron microscopy can provide images of viral particles and can be used to identify the agents.
Chandran, Vinod, Ong, Chien
core +2 more sources
New proof-of-concept in viral inactivation: virucidal efficacy of 405 nm light against feline calicivirus as a model for norovirus decontamination [PDF]
The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorganisms via ROS-generated oxidative damage.
Anderson, John G. +7 more
core +1 more source
Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain.
Malak A. Esseili +9 more
doaj +1 more source
A Dynamic Quantitative Microbial Risk Assessment for Norovirus in Potable Reuse System [PDF]
This study describes the results of a dynamic quantitative microbial risk assessment (QMRA) for norovirus (NoV) that was used to evaluate the relative significance of foodborne, person-to-person, and person-to-sewage-to-person transmission pathways. This
Ahmad, Sajjad +3 more
core +2 more sources
Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In Vitro. [PDF]
Human norovirus (HuNoV) is a major cause of nonbacterial gastroenteritis worldwide, yet despite its impact on society, vaccines and antivirals are currently lacking. A HuNoV replicon system has been widely applied to the evaluation of antiviral compounds
Emmott, Edward +4 more
core +1 more source
Production of vaccines for treatment of infectious diseases by transgenic plants
Since the first pathogen antigen was expressed in transgenic plants with the aim of producing edible vaccine in early 1990s, transgenic plants have become a well-established expression system for production of alternative vaccines against various human ...
Kristina LEDL, Zlata LUTHAR
doaj +1 more source
Chemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA viruses. [PDF]
Most antiviral treatment options target the invading pathogen and unavoidably encounter loss of efficacy as the pathogen mutates to overcome replication restrictions.
Marta J Gonzalez-Hernandez +7 more
doaj +1 more source
The norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication [PDF]
Norovirus (NoV) infections are a significant health burden to society, yet the lack of reliable tissue culture systems has hampered the development of appropriate antiviral therapies.
Cotton, Ben T +6 more
core +2 more sources
Vomiting as a Symptom and Transmission Risk in Norovirus Illness: Evidence from Human Challenge Studies. [PDF]
In the US, noroviruses are estimated to cause 21 million cases annually with economic losses reaching $2 billion. Outbreak investigations frequently implicate vomiting as a major transmission risk.
Amy E Kirby +2 more
doaj +1 more source
Background Norwalk virus causes outbreaks of acute non-bacterial gastroenteritis in humans. The virus capsid is composed of a single 60 kDa protein. In a previous study, the capsid protein of recombinant Norwalk virus genogroup II was expressed in an E ...
Takino Koichi +10 more
doaj +1 more source

