Results 51 to 60 of about 1,857,836 (187)

Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response. [PDF]

open access: yesPLoS Pathogens, 2012
Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As obligate intracellular pathogens, viruses have the capacity to manipulate the ubiquitin (Ub) cycle to their advantage by ...
Jeffrey W Perry   +5 more
doaj   +1 more source

Electronic Instrumentation in Chemical Analysis: A Case Study (and Other Examples) From a 20th‐Century “Revolution”

open access: yesNatural Sciences, Volume 6, Issue 3, July 2026.
A review of advances in chemical analysis brought about by electronic instrumentation. The techniques, and their applications, demonstrate how, collectively, they played a crucial role in transforming the laboratory landscape. If not a relatively recent revolution in one branch of science, it was certainly a transformation.
Anthony S. Travis
wiley   +1 more source

Investigation of genotype diversity of 7,804 norovirus sequences in humans and animals of China

open access: yesOpen Life Sciences, 2022
Norovirus is a prominent enteric virus responsible for severe acute gastroenteritis disease burden worldwide. In our current study, we analyzed 7,804 norovirus sequences of human and animals in China which were detected from 1980 to 2020 from GenBank ...
Li Manyu   +5 more
doaj   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

open access: yesPlant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska   +2 more
wiley   +1 more source

Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients. [PDF]

open access: yesPLoS ONE, 2011
Norwalk virus and human papilloma virus, two viruses that infect humans at mucosal surfaces, have been found capable of rapidly penetrating human mucus secretions.
Kaoru Hida   +5 more
doaj   +1 more source

Animal caliciviruses /
Calicivírus animal

open access: yesSemina: Ciências Agrárias, 2008
The caliciviruses were included in Picornaviridae family, and only in 1979 they were classified as Caliciviridae members. There are four genera included in this family: Vesivirus, Lagovirus, Norovirus and Sapovirus.
Amauri Alcindo Alfieri   +2 more
doaj   +1 more source

Waterborne Outbreak of Norwalk-Like Virus Gastroenteritis at a Tourist Resort, Italy

open access: yesEmerging Infectious Diseases, 2002
In July 2000, an outbreak of gastroenteritis occurred at a tourist resort in the Gulf of Taranto in southern Italy. Illness in 344 people, 69 of whom were staff members, met the case definition.
Della Boccia   +8 more
doaj   +1 more source

Development of Parallel Reaction Monitoring Mass Spectrometry Assay for the Detection of Human Norovirus Major Capsid Protein

open access: yesViruses, 2022
Human Norwalk viruses (HuNoVs), the most common etiological agents of acute gastroenteritis, are genetically diverse RNA viruses that frequently cause mass food poisoning internationally.
Yayoi Kimura   +11 more
doaj   +1 more source

Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 6, June 2026.
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede   +14 more
wiley   +1 more source

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