Results 71 to 80 of about 1,857,836 (187)

Bisphosphonate‐Modified Polymer‐Coated NaYF4:Yb,Er,Pr Upconverting Nanoparticles for Cell Imaging: Synthesis, Physicochemical Characterization and Biosafety

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 1, January 2026.
ABSTRACT Upconverting nanoparticles (UCNPs) have attracted much attention in nanomedicine due to their ability to upconvert photons. However, their adverse effects hinder the biomedical applications. In this paper, bisphosphonate‐modified poly(isobutylene‐alt‐maleic acid)‐graft‐poly(N,N‐dimethylacrylamide)‐coated NaYF4:Yb,Er,Pr UCNPs (UCNP@PIMAPDMA ...
Taras Vasylyshyn, Vitalii Patsula, Oleksandr Shapoval, Ognen Pop‐Georgievski, Solomiya Paryzhak, Tetiana Dumych, Victoria Serhiyenko, Nadia Skorokhyd, Olga Klyuchivska, Rafał Konefał, Jiřina Hromádková, Lucia Machová Urdziková, Dana Mareková, Aleš Benda, Pavla Jendelová, Rostyslav Stoika, Daniel Horák   +16 more
wiley   +1 more source

Disproportionate Elevated Troponin T Without Clinical Ischemia: A Diagnostic Challenge in the Emergency Department

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Background Cardiac troponins (cTns) are essential for evaluating chest pain, but elevated levels can arise from noncardiac causes or laboratory artifacts. Confirmatory testing for assay interference is often unavailable for false‐positive cases, complicating diagnosis and management.
Bryan Nicolalde, Ashraf Elamin, Dae Yong-Park, Michael DeCarolis, Samuel Hahn, Sreeja Dattachoudhury   +5 more
wiley   +1 more source

Impaired WNT3/IGF‐1 Signaling in Dorsal Dentate Gyrus Contributes to Chronic Pain‐Related Cognitive Impairment

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
Schematic diagram depicting the mechanism of SNI‐induced comorbidity of pain and cognition decline. SNI increased TNFα release in the dorsal DG (1); TNFα trigger a “double hit” to dorsal DG homeostasis: On the one hand, TNFα induced IGF‐1 resistance in granule neuron.
Yajie An, Ying Wu, Xiangyong Li, Taihe Zhou, Heming Liu, Yao Xiao, Wenyu Lai, Yuxin Qiu, Xuhong Wei   +8 more
wiley   +1 more source

Inactivation of Norwalk virus in drinking water by chlorine [PDF]

Applied and Environmental Microbiology, 1985
Norwalk virus in water was found to be more resistant to chlorine inactivation than poliovirus type 1 (LSc2Ab), human rotavirus (Wa), simian rotavirus (SA11), or f2 bacteriophage. A 3.75 mg/liter dose of chlorine was found to be effective against other viruses but failed to inactivate Norwalk virus.
B H, Keswick, T K, Satterwhite, P C, Johnson, H L, DuPont, S L, Secor, J A, Bitsura, G W, Gary, J C, Hoff   +7 more
openaire   +2 more sources

The European Union One Health 2024 Zoonoses Report

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2024 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and eight non‐MSs, according to the Zoonoses Directive 2003/99/EC.
European Food Safety Authority (EFSA) | European Centre for Disease Prevention and Control (ECDC)
wiley   +1 more source

Asymmetric Total Synthesis of (−)‐Glycybridin B, a Pharmacophore Screened Candidate for Tubulin Binding

Chemistry – A European Journal, Volume 31, Issue 55, October 1, 2025.
Discovery and first total synthesis of (−)‐glycybridin B via a five‐step route utilizing a key chalcone intermediate. Initially identified through a pharmacophore screening as a potential tubulin binder, this natural product serves as a tool compound to explore structure‐activity relationships related to microtubule targeting and anticancer potential ...
Alice Maiocchi, Maxim Shevelev, Zlata Boiarska, Juan Estévez‐Gallego, Francesca Bonato, Paolo Orlando, Alessandra Chinosi, Emanuele Marcone, Andrea Citarella, Dragos Horvath, Michel O. Steinmetz, Andrea E. Prota, Alexandre Varnek, Valerio Fasano, Daniele Passarella   +14 more
wiley   +1 more source

A Mutation‐Based Reverse Vaccinology Approach Considering Variability in Epitopes to Combat Multi‐Strains: A Study Using Glycoprotein of LASV

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Lassa virus (LASV) remains a persistent threat to public health, and to combat this, various therapeutics have been developed, but their effectiveness is limited due to the virus's strain variability. Therefore, mutation‐based reverse vaccinology approaches were implemented to formulate an epitope‐based vaccine against the LASV, considering ...
Saurav Kumar Mishra, Rajesh B. Patil, Amdola Tshering Sherpa, Mohammad Borhan Uddin, Md. Harun‐Or‐Rashid, Muniruddin Ahmed, Turki M. Dawoud, John J. Georrge   +7 more
wiley   +1 more source

Two Epidemiologic Patterns of Norovirus Outbreaks: Surveillance in England and Wales, 1992–2000

Emerging Infectious Diseases, 2003
In the period 1992–2000, the Public Health Laboratory Service Communicable Disease Surveillance Centre collected standardized epidemiologic data on 1,877 general outbreaks of Norovirus (formerly “Norwalk-like virus”) infection in England and Wales ...
Ben Lopman, Goutam K Adak, Mark Reacher, David W.G. Brown   +3 more
doaj   +1 more source

Prevalence of antibody to the Norwalk virus in various countries [PDF]

Infection and Immunity, 1979
Serum samples from children and adults from several countries were tested by radioimmunoassay for antibody to the Norwalk virus. Antibody was commonly found in adults from all the countries tested. Antibody appears to be acquired more rapidly in children from underdeveloped countries than in children from the United States.
H B, Greenberg, J, Valdesuso, A Z, Kapikian, R M, Chanock, R G, Wyatt, W, Szmuness, J, Larrick, J, Kaplan, R H, Gilman, D A, Sack   +9 more
openaire   +2 more sources

Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations

Plant Cell Reports, 2011
Despite the success in expressing a variety of subunit vaccine proteins in plants and the recent stride in improving vaccine accumulation levels by transient expression systems, there is still no plant-derived vaccine that has been licensed for human use.
Huafang Lai, Qiang Chen
semanticscholar   +1 more source