Glycerol-mediated nose-to-brain codelivery of anti-IL-17 and anti-CD73 antibodies enhances immunotherapy for melanoma brain metastases. [PDF]
Yang X +13 more
europepmc +1 more source
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best +17 more
wiley +1 more source
Urine-based nematode chemotaxis assay (N-NOSE) as a predictor of recurrence after curative surgery for resectable pancreatic cancer: preliminary data and single center experience. [PDF]
Fukada M +13 more
europepmc +1 more source
Evaluation of Systemic Inflammatory Markers in Predicting Malignancy in Parotid Gland Tumors
Preoperative systemic inflammatory indices may assist in distinguishing benign from malignant parotid tumors. In this cohort of 259 patients undergoing parotidectomy, malignant tumors were associated with higher neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) values, as well as larger tumor size and older age.
Ozcelik Erdem Rukiye +3 more
wiley +1 more source
Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases
ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen +3 more
wiley +1 more source
Lateral Mucosal Flap With Steroid‐Eluting Implant in Revision Draf Type III Frontal Sinus Surgery
This technical note introduces a novel endoscopic strategy that integrates a laterally based endonasal mucosal flap with a bioabsorbable steroid‐eluting implant to prevent restenosis following revision of Draf type III frontal sinus surgery. The vascularized flap is stabilized and maintained in close apposition to the underlying bone by a self ...
Mario Turri‐Zanoni +6 more
wiley +1 more source
Obesity and cancer: Methodological frontiers for mechanistic discoveries. [PDF]
Moore SC, Ryan PJ.
europepmc +1 more source
Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua +3 more
wiley +1 more source
Chitosan-Based Nanoparticles for Nose-to-Brain Drug Delivery: A Real Path toward Effective CNS Therapy? [PDF]
Riani LR +8 more
europepmc +1 more source
Transoral Robotic Resection of Pediatric Tongue Base Mucoepidermoid Carcinoma
Transoral robotic surgery (TORS) offers a precise, minimally invasive approach for the management of rare pediatric tongue base malignancies. Intraoperative visualization demonstrates accurate tumor delineation and controlled resection, while postoperative findings confirm effective oncologic clearance with preservation of surrounding structures.
Krisztina Somogyvári +4 more
wiley +1 more source

