Results 201 to 210 of about 204,907 (293)

Characterization of Perineural Invasion Parameters for Risk Stratification in Oral Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) is an established adverse prognostic factor in oral squamous cell carcinoma (OSCC), but the implications of its extent as well as its relationship with surgical margin status and the extent of microscopic tumor spread remain unclear.
Michael A. Müller   +7 more
wiley   +1 more source

Prognostic Impact of Lymphovascular Invasion on Distant Metastasis in HPV‐Negative Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Lymphovascular invasion (LVI) is a recognized poor prognostic factor in head and neck squamous cell carcinoma (HNSCC), particularly for regional recurrence and overall survival. However, its role in predicting distant metastasis, especially in HPV‐negative HNSCC, remains unclear. Objective To evaluate the association between LVI and
Mark Khoury   +11 more
wiley   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt   +7 more
wiley   +1 more source

Quality of Life Among Patients with Nasal Obstruction-Does Etiology Matter? [PDF]

open access: yesJ Clin Med
Chvatinski L   +8 more
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

open access: yesJournal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Adaptive Immunity in Marsupials

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol   +2 more
wiley   +1 more source

Impact of Breast Cancer Surgery on Physical Well-Being of the Chest: A Longitudinal BREAST-Q Study. [PDF]

open access: yesPlast Reconstr Surg
Marco E   +9 more
europepmc   +1 more source

3D Printing a Clinically Available Solution From Plaster‐Based Positives in Superficial Radiation Therapy

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This study compares two techniques for creating lead shielding masks to replace the current process for superficial/orthovoltage facial radiotherapy: Plaster Cast Positive Mould (PCPM), CT Scanned 3D Print (CT3DP), and Optical Scan 3D Print (OS3DP). CT3DP was found to be more accurate and preferred over OS3DP.
Rory Hartley   +6 more
wiley   +1 more source

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