ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley +1 more source
First worldwide comparison of right hemicolectomy for colon cancer using vaginal natural orifice transluminal endoscopic surgery (VNOTES) versus transvaginal natural orifice specimen extraction surgery (TVNOSE). [PDF]
Seow-En I +4 more
europepmc +1 more source
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
OSIRIS-Nose: Organ Sparing Using Interventional Radiotherapy (Brachytherapy) for Invasive Squamous Cell Cancer of the Nasal Vestibule. [PDF]
Soror T +6 more
europepmc +1 more source
Open or closed: Experience of head and neck radiotherapy masks – A mixed‐methods study
Patients with head and neck cancer received radiotherapy alternately with an open and a closed mask. The closed mask was perceived as more confining and restrictive, but it was also considered to make it easier to quickly achieve the correct position, while the open mask was perceived as less stable, although it reduced the feeling of claustrophobia ...
Erik Lundin +2 more
wiley +1 more source
Xeroderma pigmentosum associated with recurrent squamous and basal cell carcinoma: a case report from Nepal. [PDF]
Paudel P +7 more
europepmc +1 more source
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley +1 more source
Development and preliminary validation of a multidisciplinary 3D‑printed skull base model for endoscopic endonasal surgical training. [PDF]
Sanz-Peña B +6 more
europepmc +1 more source
ABSTRACT Background Patients with early‐stage cutaneous melanoma (CM) have low individual risk but account for most distant recurrences. The utility of gene expression profiling (GEP) in CM risk stratification and clinical management remains unclear. Methods From 2015 to 2022, CM patients at a single center were universally referred for DecisionDx 31 ...
Daniel B. Gehle +10 more
wiley +1 more source
Nasal septal perforation in pregnancy case report: A family medicine perspective. [PDF]
Mughal Z +3 more
europepmc +1 more source

